Ridiculous Dietary Allowance
Many people consuming RDA levels of vitamins are likely to suffer from deficiency disease and premature death. Current official recommendations for nutrient intakes are inappropriate. As this book demonstrates, the recommended dietary intake for vitamin C owes more to politics and prejudice than to science. Furthermore, the research behind the RDA values for vitamin C is biased and insubstantial. This book presents an open challenge to the government "experts," who support the out-of-date RDA approach to nutrition and thereby endanger the health of the entire population. For people who value the peer review process, this book was read by thousands, including doctors and scientists. The readers reported no significant scientific errors. The authors therefore assert that the RDA and the Codex justification for low intakes of vitamin C are both invalid and indefensible.
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Vitamin C in the body
Low dose hypothesis
High dose hypothesis
White blood cells
Benefits of high doses
Costs and benefits
Quantifiable biomarkers for scurvy
70 microM/L 90mg per day absorbed absorption acute scurvy amount antioxidant ascorbate concentration ascorbate levels ascorbate transporters ascorbic acid atherosclerosis baseline benefits bias bioavailability blood plasma blood vessels body pool body tissues bowel tolerance cancer Cathcart’s committee’s concentration of ascorbate cost-benefit analysis deficiency disease dehydroascorbate doses of ascorbate doses of vitamin drug dynamic flow model enzyme estimate evidence excreted explanation GLUT4 gram level grams grams per day half-life heart disease high-dose higher doses human increase indicate Institute of Medicine Irwin Stone kidney levels of ascorbate Linus Pauling low dose hypothesis low intakes measure mM/L neutrophils nutrients oral dose oxidation oxidised pharmacokinetic pharmacological physiological plasma concentrations plasma levels population prevent RDA committee RDA justification RDA values Recommended Dietary Allowance risk Robert Cathcart saturation scientific scientists scurvy short half-life side effects specialised steady studies suggest three grams tolerable upper limit toxicity white blood cells
Page 149 - Antioxidant vitamins and mortality in older persons: findings from the nutrition add-on study to the Medical Research Council Trial of Assessment and Management of Older People in the Community. Am J Clin Nutr 2003;78:999-1010.