Schistosomiasis: The St Lucia Project

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CUP Archive, Nov 7, 1985 - Medical - 442 pages
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Schistosomiasis is a disease affecting over 200 million people in developing countries. It is caused by worms that need particular species of fresh water snails for completing their life cycle, and developments in Third World countries have spread and increased the severity of the disease. Dr Jordan describes a 15 year study on St Lucia, a mountainous Caribbean Island where isolated valleys provided ideal field laboratories for comparing the effects on transmission, the advantages and disadvantages of intensive snail control, environmental improvement (providing villages with water), and chemotherapy with newly available drugs. The project was staffed by a multidisciplinary team and their intensive programme led to successful control. This book describes the investigation, fully and readably. It will be valuable to all who work in the fields of tropical medicine, parasitology, epidemiology, community and environmental health, and vital to workers on schistosomiasis control in developing countries.
 

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Contents

Introduction
1
The island of St Lucia
9
Snail intermediate hosts and schistosomiasis in
31
The strategic plan and methods of investigation
44
Untreated comparison areas
71
Chemotherapy in control
92
Control of the intermediate snail host
116
Fond St Jacques
166
Summary and recommendations
255
Comparison of control strategies
268
Drug trials
289
Molluscicide trials
307
Biological control
327
Epidemiology
340
Immunological studies Dr D G Colley
379
Balanced incomplete block design for studying water contact
398

Parasitological surveys
173
Summary and recommendations
181
Calypso area
233
Biological studies
247
Identification of freshwater fish killed by molluscicide
404
INDEX
429
Copyright

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Popular passages

Page 410 - Immune responses during human schistosomiasis mansoni. I. In vitro lymphocyte blastogenic responses to heterogeneous antigenic preparations from schistosome eggs, worms and cercariae. Int.
Page 422 - Asofsky, R., 1982. Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae. II. Analysis of immunity in hosts deficient in T lymphocytes, B-lymphocytes or complement.
Page 407 - KS WARREN. 1964. Mild prolonged schistosomiasis in mice: alterations in host response with time and the development of portal fibrosis. Trans. Roy. Soc. Trop. Med. Hyg. 58: 53-57.
Page 412 - Changing host granulomatous response to schistosome eggs at different stages of infection with Schistosoma mansoni. Am. J. Pathol., 52: 369-377.
Page 410 - COLLEY, DG 1975. Immune responses to a soluble schistosomal egg antigen preparation during chronic primary infection with Schistosoma mansoni. J. Immunol. 115: 150— 156.

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About the author (1985)

PETER JORDAN has had a lifelong interest in mushrooms. He runs a world-renowned public house in rural Norfolk, England, where he has devoted his time to collecting mushrooms and cooking them for his customers to enjoy. Peter has produced a video, The Collector's Guide to Wild Mushrooms, and he spends time writing for television and running The Tasty Mushroom Partnership.

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