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Design and Objectives
Relation between Objectives and Designs
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activity acute antibody aquatic assay biological Cancer Inst carcinogens cause cells chamber chemical chronic clinical colony compound concentration contamination detect diet disease dose level drug effect examined example experiment experimental exposure factors female genetic hepatocytes human immune important incidence induced infectious agents investigators involved laboratory animals lesions liver long-term lung lymphocytic choriomeningitis lymphocytic choriomeningitis virus mammalian mammary mammary tumors measured methods mice monitoring mouse hepatitis virus murine mutagenic mutation Mycoplasma pulmonis Natl necropsy observations occur organ Pasteurella pneumotropica Pathol pathologist pathology Pharmacol potential problems procedures produce protocol quality control renal respiratory response rodents safety evaluation sample SDAV selected Sendai virus serum species spontaneous Sprague-Dawley Sprague-Dawley rat standard statistical strains substance susceptible techniques teratogenic teratological studies Teratology test material tissue TOSCA toxicity toxicity testing Toxicol toxicological research toxicology treatment tumors vapor viral virus infection viruses