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The Molecular Genetics of Hemoglobin By PETER T CURTIN and YUET
Regulatory Regions Flanking the Human Fetal 7Globin Genes By HENRY
The Emerging Complexity of Genetic Control of Persistent Fetal Hemoglobin
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abnormal Acad adhesion adolescents adult analgesics B-globin behavior Biol Biophys blood cells capillaries cation cellular cetiedil child children with sickle chronic Clin clinical decrease deﬁned dehydration delay density deoxygenation drug effect endothelium erythrocytes erythroid factors fetal hemoglobin ﬁbers FIGURE ﬁndings ﬁrst ﬂow ﬂuxes function G. R. SERJEANT g/dl gelation genetic globin gene Haematol haplotype Hb SS HbF levels hematological hemoglobin concentration hemoglobinopathies HOFRICHTER homozygous human identiﬁed increased inﬂuence inhibition interaction intracellular irreversibly sickled cells kinetics MCHC membrane microvascular modiﬁed Molecular mutation normal opioid oxygen painful crisis patients with sickle Pediatr phospholipids plasma polymer polymerization population prenatal diagnosis Proc promoter protein R. L. NAGEL red cells rheological Saudi sequences shear sickle cell anemia sickle cell disease sickle cell patients sickle cell trait sickle erythrocytes sickle hemoglobin signiﬁcant signiﬁcantly speciﬁc SS cells SS patients studies syndrome thalassemia transfusion vasoocclusive viscosity