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Factors Affecting Sorption of Topically Applied Substances
In Vivo Methods for the Assessment of Percutaneous Absorption in Man
In Vitro Methods for Measuring Skin Permeation
10 other sections not shown
absorbed acid activity amount animal aqueous assess barrier benzocaine benzoic acid binding blood level Bronaugh buffer chemical clinical compared compounds concentration cosmetic cutaneous dermis diffusion cell donor dosage forms drug delivery effect epidermis Equation estradiol ethanol evaluated excretion experimental exposure factors Figure flux hairless mouse skin Hl Maibach horny layer hydration hydrocortisone in-vitro in-vivo increase infinite dose interaction Invest Dermatol iontophoresis lidocaine lipid liposomal liposomal formulations measured mechanism membrane metabolism methods molecular molecules nitroglycerin nonionic occlusion oleic acid optimized parameters partition coefficient penetration enhancers percutaneous absorption permeability Pharm Sci polymer potential properties propylene glycol radioactivity rat skin receptor fluid release skin skin penetration skin permeation skin surface solubility solution solvent sorbed sorption steroid stratum corneum stripping studies substances surfactants Table technique temperature therapeutic tion tissue topical products topically applied transdermal system transport uptake values vehicle vitro vivo