Annual Review of Gerontology and Geriatrics, Volume 10, 1990: Biology of Aging

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Vincent J. Cristofalo, PhD
Springer Publishing Company, Nov 15, 1990 - Medical - 290 pages
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This volume presents a clear, concise overview of the current state of knowledge about the biology of aging serving as both an invaluable graduate-level text and a key reference for practicing professionals. Over a dozen distinguished contributors probe the latest developments in our knowledge of why people age and how the process works. These authoritative chapters are not just written for biologists but for gerontologists in general. Marks the tenth anniversary of the Annual Review of Gerontology and Geriatrics.

 

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Contents

Chapter 1 Overview of Biological Mechanism of Aging
1
Chapter 2 Genetic Diseases of Premature Aging as Models of Senescence
23
Chapter 3 Growth Factors and Cell Aging
43
Chapter 4 Role of Endogenous Proteins as Negative Growth Modulators During In Vitro Cellular Aging of Human Diploid Fibroblasts
53
Mechanisms of Decline
71
Chapter 6 Molecular Genetic Approaches to Mechanisms of Senescence
97
Chapter 7 Altered Protein Metabolism in Aging
117
From Receptors to Calcium Mobilization
132
Underlying Mechanisms
147
Widespread Involvement of All Three Major Filament Systems
167
Chapter 11 Dietary Restriction as a Probe of Mechanisms of Senescence
183
Chapter 12 Role of Free Radicals in Senescence
198
Index
215
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