Statins in General Practice: Pocketbook
The use of statins in clinical practice has become an established part of modern medicine. They were introduced in the late 1980s and early 1990s as a new group of cholesterol-lowering drugs, but have since become agents that have an important effect in reducing not only blood lipid levels but also an individual's risk of vascular disease. The aim
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acid sequestrant resin acute analysis apolipoprotein atherosclerosis atherosclerotic plaque atorvastatin baseline bile acid sequestrant cardiovascular disease cardiovascular events Cerivastatin CHD risk cholesterol levels cholesterol lowering cholesterol reduction Cholesteryl ester clinical trial CoA reductase inhibitor coronary arteries coronary events coronary heart disease Coronary Prevention Study death density lipoprotein diabetes drugs dyslipidaemia effects of pravastatin endothelial enzyme fats fatty acids fatty streak Framingham global risk HMG CoA reductase hypercholesterolaemia hyperlipidaemia hypertension important increased inflammatory inhibiting LDL cholesterol LDL receptor lesion lipid lipid lowering lipid profile Lovastatin low HDL major metabolism mg/dl myocardial infarction non-fatal oxidation placebo plasma cholesterol plasma triglyceride post-MI patients pravastatin therapy Prevention of coronary primary prevention primary-care randomized revascularization risk assessment risk factors risk reductions rupture secondary prevention serum cholesterol Sheffield tables simvastatin smooth muscle cells statin therapy stroke subjects thrombus total cholesterol total mortality treatment triglyceride vascular disease VLDL West of Scotland WOSCOPS