The BMT Data Book: Including Cellular Therapy

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Reinhold Munker, Gerhard C. Hildebrandt, Kerry Atkinson
Cambridge University Press, Feb 21, 2013 - Medical - 543 pages
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This is an essential guide to the data, basic science, outcome studies and decision-making processes involved in blood and marrow stem cell transplantation. Organized according to disease types and procedures, it contains more than 100 tables, figures and algorithms that reflect up-to-date research and give guidance on the choices between different types of chemotherapy, autologous vs. allogeneic transplantation, peripheral blood vs. bone marrow stem cells, and standard vs. experimental treatments. This new edition summarizes the research of the last four years and gives mature data for all established indications, such as acute myeloid leukemia, myelodysplastic syndrome and Hodgkin and non-Hodgkin lymphomas. New chapters discuss global trends in stem cell transplantation, cellular therapies including donor lymphocytes, and pediatric neurologic and metabolic disorders. With an expanded complications section, links to electronic databases and discussion of new drugs and alternative stem cell sources, this text belongs in every transplant unit.
 

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Contents

Hematopoietic cell transplantation past present and future
1
Basic science
7
Therapeutic decision making in BMTSCT for acute myeloid leukemia
25
Therapeutic decision making in BMTSCT for acute lymphoblastic leukemia
41
Therapeutic decision making in BMTSCT for chronic myeloid leukemia and other myeloproliferative syndromes
56
Therapeutic decision making in BMTSCT for chronic lymphatic leukemia
67
Therapeutic decision making in BMTSCT for myelodysplasia
77
Hematopoietic cell transplantation for nonHodgkin lymphoma
90
Therapeutic decision making in BMTSCT for congenital immunodeficiencies
172
Therapeutic decision making in BMTSCT for hemoglobinopathies
179
HSCT for inborn errors of metabolism and neurodegenerative disorders
192
Therapeutic decision making in BMTSCT for autoimmune disorders
205
Cellular therapy
209
Practical aspects and procedures including conditioning protocols and haploidentical transplantation
235
Umbilical cord blood as an alternative allogeneic graft source clinical banking and transplant outcomes
288
Pathobiology of graftversushost disease
297

Therapeutic decision making in BMTSCT for Hodgkin lymphoma
113
Therapeutic decision making in hematopoietic SCT for multiple myeloma
122
Therapeutic decision making in SCT for amyloidosis
133
Therapeutic decision making in BMTSCT for nonseminomatous germ cell tumor of testis
139
Therapeutic decision making in BMT SCT for renal cell cancer
146
Therapeutic decision making in BMTSCT for soft tissue sarcomas
159
Therapeutic decision making in BMTSCT for severe aplastic anemia
165
Diagnosis and treatment of graftversushost disease
311
Management and prophylaxis of infections after BMTSCT
330
Organrelated and miscellaneous complications
348
The BMTSCT pharmacopoeia
411
HLAtesting and laboratory medicine
509
Index
529
Copyright

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About the author (2013)

Reinhold Munker, MD is Associate Professor of Medicine, Department of Medicine, Division of Hematology-Oncology, Louisiana State University, Shreveport, LA, USA.

Gerhard C. Hildebrandt, MD is Associate Professor of Medicine, Department of Medicine, Division of Hematology-Oncology, Louisiana State University, Shreveport, LA, USA.

Kerry Atkinson, MD, FRCP, FRACP is Professor of Medicine, Division of Hematology-Oncology, University of Queensland, and Head, Stem Cell Biology, Regenerative Medicine and Novel Therapeutic Anti-Cancer Agents Group, Mater Medical Research Institute, Queensland, Australia.

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