The Biology of CancerThoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world.The Biology of Cancer is a textbook for students studying the molecular and cellula |
Contents
1 | |
31 | |
Tumor Viruses | 71 |
Cellular Oncogenes | 103 |
Growth Factors Receptors and Cancer | 131 |
Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer | 175 |
Tumor Suppressor Genes | 231 |
pRb and Control of the Cell Cycle Clock | 275 |
Multistep Tumorigenesis | 439 |
Maintenance of Genomic Integrity and the Development of Cancer | 511 |
Heterotypic Interactions and the Biology of Angiogenesis | 577 |
Moving Out Invasion and Metastasis | 641 |
Crowd Control Tumor Immunology and Immunotherapy | 723 |
The Rational Treatment of Cancer | 797 |
Abbreviations | 877 |
Glossary | 1 |
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Common terms and phrases
ability actions activated addition alleles alterations apoptosis appear associated become binding blue breast cancer cells carcinoma carry causes cell cycle cellular changes Chapter chromosomal colon complex components copies create cyclin cytoplasmic depend detected differentiation distinct domain effects encoding enzyme epithelial cells example experiments expression fact Figure formation function gene genetic genome green growth factor human important inactivation increased indicated individual induce infected initially involved kinase lead levels ligand loss major mechanisms membrane mice molecules mouse mutations normal observed occur once oncogene organism pathway patients phenotype population present progression proliferation promoter proteins receptor relatively repair replication responsible resulting revealed role seen sequences shown Sidebar signaling specific stem cells stroma structure suggests suppressor telomeres termed tion tissues transcription transformed tumor tumor cells types variety various viral virus