The Epigenome: Molecular Hide and Seek

Front Cover
Stephan Beck, Alexander Olek
John Wiley & Sons, Mar 6, 2006 - Science - 188 pages
This is the first book that describes the role of the Epigenome (cytosine methylation) in the interplay between nature and nurture. It focuses and stimulates interest in what will be one of the most exciting areas of post-sequencing genome science: the relationship between genetics and the environment.
Written by the most reputable authors in the field, this book is essential reading for researchers interested in the science arising from the human genome sequence and its implications on health care, industry and society.
 

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Contents

1 Five Not Four History and Significance of the Fifth Base
3
2 Epigenetic Signals Towards a Human Genome Sequence of All Five Nucleotides
23
3 Epi Meets Genomics Technologies for Finding and Reading the 5th Base
41
4 Mammalian Epigenomics Reprogramming the Genome for Development and Therapy
67
5 At the Controls Genomic Imprinting and the Epigenetic Regulation of Gene Expression
81
6 Epigenetic Trouble Human Diseases Caused by Epimutations
103
7 Liver or Broccoli? Foods Lasting Effect on Genome Methylation
119
8 Living Longer The Aging Epigenome
141
9 Digitizing Molecular Diagnostics Current and Future Applications of Epigenome Technology
153
Subject Index
175
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About the author (2006)

Stephan Beck is the editor of The Epigenome: Molecular Hide and Seek, published by Wiley.

Alexander Olek is the editor of The Epigenome: Molecular Hide and Seek, published by Wiley.

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