The Genetics of Obesity
This book provides a comprehensive compilation of the evidence available regarding the role of genetic differences in the etiology of human obesities and their health and metabolic implications. It also identifies the most promising research areas, methods, and strategies for use in future efforts to understand the genetic basis of obesities and their consequences on human health. Leading researchers in their respective fields present contributed chapters on such topics as etiology and the prevalence of obesities, nongenetic determinants of obesity and fat topography, and animal models and molecular biological technology used to delineate the genetic basis of human obesities. A major portion of the book is devoted to human genetic research and clinical observations encompassing adoption studies, twin studies, family studies, single gene effects, temporal trends and etiology heterogeneity, energy intake and food preference, energy expenditure, and susceptibility to metabolic derangements in the obese state. Future directions of research in the field are covered in the book as well.
What people are saying - Write a review
We haven't found any reviews in the usual places.
Nongenetic Determinants of Obesity and Body Fat Topography
Twin Studies of Human Obesity
Identification of Genes Underlying Polygenic Obesity in Animal Models
Etiologic Heterogeneity and Temporal Trends
abnormalities adipocytes adipose tissue adoption studies adult animal models associated behavior biological body composition body fat body mass index body weight Bouchard candidate genes cholesterol chromosome Clin cloning correlations determinants diabetes diabetes mellitus diet dietary differences disease dyslipidemia energy balance energy expenditure energy intake environment environmental factors estimated expression familial resemblance Family Study fat distribution fat mass genetic effect genetic factors genetically obese genome genotype glucose transporter GLUT4 heritability human obesity hyperinsulinemia hypertension identify increase individuals influences inheritance insulin resistance levels linkage lipid lipoprotein lipase loci major gene mapping markers measured mice molecular mouse mRNA mutations MZ twins NIDDM nongenetic Nutr nutrient obesity obesity genes obesity phenotypes overfeeding overweight pairs parents Pérusse physical activity polygenic preadipocytes protein receptor response segregation analysis siblings single gene skinfolds Stunkard suggest syndrome trait transmission Tremblay triglyceride twin study variance variation visceral fat
Page 220 - Neel JV: Diabetes mellitus: A 'thrifty' genotype rendered detrimental by 'progress'?
All Book Search results »