The HDL Handbook: Biological Functions and Clinical Implications

Front Cover
Tsugikazu Komoda
Academic Press, Sep 6, 2010 - Medical - 296 pages

The HDL Handbook: Biological Functions to Clinical Implications brings laboratory research in HDL from bench to bedside in this needed resource for researchers and clinicians studying cholesterol, lipids, epidemiology, biochemistry, molecular medicine, and pathophysiology of cardiovascular diseases. In addition, researchers and clinicians working with an aging population, corporate researchers, post-doctorates; medical students and graduate students will find this publication useful because the scope of coverage includes basic science, genetics, epidemiology, and treatment of HDL cholesterol as well as potential targets to modify HDL cholesterol.

  • Comprehensive coverage of basic science, genetics, epidemiology and treatment
  • Reputable content on latest advances in HDL cholesterol research
  • Inclusive, worldwide content with country specific information
  • In depth discussion of potential targets to modify HDL
 

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Contents

Chapter 2 The Role of Cholesteryl Ester Transfer Protein CETP in HDL Metabolism
17
Chapter 3 Plasma Cholesteryl Ester Transfer Protein CETP in Relation to Human Pathophysiology
35
Physiological Modulation
61
Relationship between PON1 and Oxidative Stress
77
Molecular Structures ofnbspPON1nbspand HDL
99
Chapter 7 Apolipoprotein AI Mutations
133
An HDL Receptor Involved in Lipid Transport and HDL Dependent Signaling
153
Novel Therapeutic Strategies for the Treatment of Inflammatory Vascular Disease
179
Chapter 10 Sterol Efflux by ABCA1 and ABCG1
199
Chapter 11 Functional Change in the HDL Particle by Oxidative Modification and its Contribution to Atherogenesis
215
Chapter 12 Prebeta1HDL a Native Lipidpoor HDL and its Potential asnbspanbspNew Marker for HDL Metabolism
243
Chapter 13 Determination of Circulating Native and Denaturated HDL Concentrations and its Clinical Implications
261
Index
277
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About the author (2010)

Dr. Komoda is a visiting professor at Toho University School of Medicine in Japan. He has extensive expertise with research in alkaline phosphatase, amylase, and oxidized HDL. He co-operated the intestinal alkaline phosphatase at Washington University School of Medicine in St. Louis, Missouri. He is the recipient of the Kodama Memorial Award from Japanese Society of Electrophoresis.

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