The Kidney: From Normal Development to Congenital Disease
Peter D. Vize, Adrian S. Woolf, Jonathan B.L. Bard
Elsevier, Mar 14, 2003 - Science - 592 pages
Organogenesis of the kidney has been intensely studied for over a century. In recent years advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began to unravel the molecular basis of many forms of congenital kidney disease. This book is a comprehensive study on these findings and the only book available with such in depth coverage of the kidney.
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abnormalities acid activity adult apical apoptosis basement membrane basolateral branching capillary Cell Biol collagen collecting duct culture cysts defects developing kidney developmental differentiation distal tubule domain Dressler Drosophila embryos encoding endothelial cells epithelial cells epithelium fetal filtration foot processes formation function GDNF gene expression Genet glomerular glomeruli growth factor human induced inhibition integrin interactions intermediate mesoderm kidney development Kidney Int laminin mature mesenchyme mesonephric mesonephros metanephric mesenchyme mice molecular molecules morphogenesis mouse mRNA mutations neonatal nephric duct nephrogenesis nephrogenic nephron nephrostomes normal organ pathway patients patterning Pax genes Pax2 Pediatr phenotype Physiol podocytes polycystic kidney disease postnatal pronephric tubules protein proximal tubule reabsorption receptor regulation renal role segments signaling sodium somites stage stromal structure syndrome targeted tissue transcription factor transgenic transport tubular tubulogenesis tumor suppressor ureter ureteric bud urinary urogenital vascular vitro Vize Wilms Wolffian Wolffian duct Xenopus zebrafish