The Liver: Biology and Pathobiology

Front Cover
Irwin M. Arias, Allan W. Wolkoff, James L. Boyer, David A. Shafritz, Nelson Fausto, Harvey J. Alter, David E. Cohen
Wiley, Sep 24, 2009 - Medical - 1216 pages
In its Fifth Edition, this classic book retains its traditional strength of relating molecular physiology to understanding disease pathology and treatment as it explores the current state and future direction of hepatology.

Painstakingly revised, this edition includes 60 new chapters. As in previous editions, a section called Horizons summarizes advances of extraordinary nature in areas expected to have a substantial impact on hepatology. The Fifth Edition’s Horizons section includes emerging topics such as tissue engineering of the liver, liver-directed gene therapy, decoding the liver cancer genome, and imaging cellular proteins and structure.

To preserve essential background information which has not changed while making room for the panoply of major new contributions to understanding of liver disease, 14 chapters from the previous edition are freely available online at To view these chapters visit -

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About the author (2009)


Irwin Arias, MD, National Institutes of Health, Bethesda, Maryland. Professor of Physiology, Emeritus, Tufts University School of Medicine, Boston, Mass. Visiting Professor of Medicine, Albert Einstein College of Medicine, Bronx, NY.

Associate editors:

James L. Boyer, Yale University School of Medicine, New Haven, CT, USA

David Shafritz, Albert Einstein College of Medicine, Bronx, NY, USA

Nelson Fausto, Professor and Chair, Department of Pathology, University of Washington, Seattle, WA, USA.

Harvey Alter, Department of Transfusion Medicine, National Institutes of Health, Bethesda, Maryland, USA

David E. Cohen,.Division of Gastroenterology, Brigham and Women's Hospital, Boston, Massachusetts, USA

Allan Wolkoff, Albert Einstein College of Medicine, Bronx, NY, USA

Bibliographic information