The Progress of Experiment: Science and Therapeutic Reform in the United States, 1900-1990This book explores the origins of our contemporary system of drug regulation and the modern clinical trial. Marks illustrates the symbiotic relationship between the history of modern drug regulation and the history of therapeutic reform. Accompanying this history of public policy is a detailed account of changing experimental ideals and practices. Marks traces the history of therapeutic experimentation, from the "collective investigations" of the past century to the controlled clinical trial that emerged after 1950 as the paradigm of scientific experimentation. The result is the first general history of clinical research in the United States, a book that examines therapeutic experiments in a wide range of diseases, from syphilis and pneumonia to heart disease and diabetes. |
What people are saying - Write a review
Reviews aren't verified, but Google checks for and removes fake content when it's identified
User Review - Flag as inappropriate
23 nostrums
Contents
A rational therapeutics | 17 |
Memories of underdevelopment Therapeutic research in the United States 19001935 | 42 |
Playing it safe The Federal Food Drug and Cosmetic Act of 1938 | 71 |
War and peace | 98 |
Of methods and institutions or The triumph of statistics | 129 |
Managing chance Statistics and therapeutic experiments 19501960 | 136 |
You gotta have heart | 164 |
Anatomy of a controversy The University Group Diabetes Program study | 197 |
The dreams of reason Retrospect and prospect | 229 |
A NOTE ON SOURCES | 249 |
INDEX | 251 |
Other editions - View all
The Progress of Experiment: Science and Therapeutic Reform in the United ... Harry M. Marks No preview available - 1997 |
The Progress of Experiment: Science and Therapeutic Reform in the United ... Harry M. Marks No preview available - 1997 |
Common terms and phrases
Administration American analysis Association August authority Bulletin Cambridge century Chemistry claims clinical research Clinical Trials Committee concerns conducted controlled cooperative Council critics December decision Diabetes diet dietary differences difficulties discussion drug early effects evaluation evidence experiment experimental February Federal findings Food Fund glucose heart disease History Hospital Human individual industry initial Institute interest issue JAMA January John Journal July June Keys knowledge laboratory less Long manufacturers March means Medical Research Medicine Meeting methods Minutes Myocardial Infarction November October officials organization patients penicillin physicians planning Pneumonia political practice prevention problem proposed Public Health question randomized records reformers regarding regulation Report scientific serum social standards statistical statisticians streptomycin syphilis therapeutic therapeutic reformers Therapy tolbutamide treating treatment UGDP United University Press W-NRC World York