The Sunburnt appearance of the skin as an early diagnostic symptom of supra renal capsule disease

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Miller & Holman, 1856 - 21 pages
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Page 3 - This discoloration pervades the whole surface of the body, but is commonly most strongly manifested on the face, neck, superior extremities, penis, and scrotum, and in the flexures of the axillae and around the navel.
Page 3 - ... surmounted by further experience in this, I fear, irremediable disease, is a correct and certain diagnosis; — how we may at the earliest possible period detect the existence of this form of anaemia, and how it is to be distinguished from other forms of anaemic disorder. As I have already observed, the great distinctive mark of this form of anaemia is the singular dingy or dark discoloration of the skin; nevertheless at a very early period of the disorder, and when the capsules are less extensively...
Page 19 - ... abundantly supplied with nerves and cells, very like the ganglion-globules, represents the other divisions of the sympathetic ganglia: whence he concludes that Bergmann's view, according to which the suprarenal capsules are closely related to the nervous system, is undoubtedly correct, and that those organs bear the same relation to the ganglia, of the sympathetic nerves, as the pituitary body bears towards the brain. Besides this relation to the nervous system, however, they have an intimate...
Page 4 - ... certainty in others. It must, however, be observed, that every tinge of yellow, or mere sallowness, throws a still greater doubt over the true nature of the case, and that the more decidedly the discoloration partakes of the character described, the stronger ought to be our impression as to the capsular origin of the disorder.
Page 3 - ... and in one instance the skin was so universally and so deeply darkened that but for the features the patient might have been mistaken for a mulatto.
Page 18 - The conclusion to which he has arrived, is that in view of the absence of all physiological indications, and so long as the course of the nerves in them is not more accurately known, only very general deductions can be offered. But he considers " The cortical and medullary substance as physiologically distinct...
Page 16 - ... coloring matter found to be deposited in a granular form, and could not be distinguished from a mulatto, and it .is believed that it is recognized that the color in the mulatto is dependent upon a special arrangement in the organization of a certain tissue of the skin ; that pigment cells of a dark color is secreted in the form of fine granular matter, instead of being uniformly diffused through the tissues. Respecting the anatomy of these organs, we know that different opinions have been entertained...
Page 14 - It resembles strikingly the color of a bronzed statue from which the gloss has been rubbed off. Pressure has no effect in causing its diminution. It seems as a rule to commence first in patches with ill-defined borders, on those parts...
Page 17 - Kokitansky has observed that accessory supra renal capsules, indicating an apparent excess of development, are of frequent occurrence, and several flattened accessory capsules are then found on the renal and solar plexus, and on the ganglion of the latter nerve, varying in size from a millet to a hemp seedIn the morbid anatomy of the cases reported by Dr.
Page 4 - ... negative evidence; and when we fail to discover any of the other wellknown sources of that condition, when the attendant symptoms resemble those enumerated as accompanying disease of the capsules, and when to all this is superadded a dark, dingy, or smoky-looking discoloration of the integument, we shall be justified at least in entertaining a strong suspicion in some instances, a suspicion almost amounting to a certainty in others.

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