The Biology of the Autistic Syndromes

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Cambridge University Press, Jan 18, 2000 - Medical - 330 pages
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Autism is not a single disease but a syndrome of different diseases. In this completely reworked and updated third edition, two world authorities, Christopher Gillberg and Mary Coleman, address the difficulties this presents for clinical diagnosis with diagnostic aids and clear guidelines for medical evaluation. Epidemiology, neuropsychological studies and behavior complexes, such as self-injury, are reviewed in detail, and the authors give a detailed explanation of what is known about the molecular biology and genetics of autism. Epilepsy and electrophysiological studies are also covered, as well as biochemistry, endocrinology, immunology, brain imaging and neuropathology. The available medical therapies are reviewed, along with an update on what is known about other interventions, such as psychoeducational and behavioral modification procedures. The book concludes with an integration of current knowledge from diverse fields. This is an essential text for clinicians and will also be of interest to parents of autistic children.
 

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Contents

INTRODUCTION
1
CLINICAL DIAGNOSIS
4
ASPERGER SYNDROME
39
DIAGNOSIS IN INFANCY
53
CLINICAL COURSE IN CHILDHOOD AND ADOLESCENCE
63
ADULTS WITH AUTISM
73
ADDITIONAL BEHAVIORS SEEN IN NDMDUALS WITH AUTISM
79
THE EPIDEMIOLOGY OF AUTISM AND ITS SPECTRUM DISORDERS
85
BIOCHEMISTRY ENDOCRNOLOGY AND IMMUNOLOGY
197
STRUCTURAL INFORMATION FROM BRAIN IMAGING AND NEUROPATHOLOGY
217
THE GENETICS OF AUTISM
232
THE FIRST NEUROPSYCHIATRIC ASSESSMENT
262
MEDICAL THERAPIES
269
OTHER INTERVENTIONS
286
THE NEUROLOGY OF AUTISM
291
GLOSSARY OF GENETIC TERMS
310

NEUROPSYCHOLOGY IN AUTISM AND ITS SPECTRUM DISORDERS
102
THE DISEASE ENTITIES OF AUTISM
118
DOUBLE SYNDROMES
136
EPILEPSY AND ELECTROPHYSIOLOGY
185
CHARTER FOR PERSONS WITH AUTISM
314
INDEX
316
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