Time-of-Flight Mass Spectrometry and its Applications
Newnes, Dec 2, 2012 - Science - 424 pages
The resurgence of time-of-flight mass spectrometry (TOF-MS) has had its origin in the simplicity of construction and application of such instruments together with the high transmission and the great increase in resolution that has been achieved. The instrument lends itself naturally to a coupling with pulsed laser sources, though this is not a prerequisite. It also affords a time resolution far beyond that traditionally achieved with mass spectrometric rapid scan techniques - a recent example being the real-time analysis of a multi-component mixture from an automobile exhaust. Furthermore, the mass range appears to be extremely large: mass up to 500 kDa and beyond what is being readily measured in the laboratory today.
The present set of contributions attempts to give a survey of current applications from many of the active groups in the field. A variety of new applications are considered which are no doubt just the beginning of large new areas of application. By presenting this work in book form it is hoped that it will be of help to the many groups intending to initiate work in this rapidly expanding new area of mass spectrometry.
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Chapter 3 The application of ion optics in timeofflight massspectrometry
Chapter 4 Design considerations in energy resolved timeofflightmass spectrometry
Chapter 5 Laser ion sources for timeofflight mass spectrometry
an examinationof experimental consequences
Chapter 7 Highresolution mass spectrometry in a lineartimeofflight mass spectrometer
Chapter 8 The design and performance of an ion trap storagereflectron timeofflight mass spectrometer
Chapter 14 Quantitative determination of kinetic energy releasesfrom metastable decompositions of sputtered organicions using a timeofflight mass s...
application of time of flight methods to clusters and pyrolysis studies in supersonic expansions
Chapter 16 Photodissociation of magnesium ionmolecule complexes in a reflectron timeofflight mass spectrometer
Chapter 17 Resonanceenhanced twophoton ionizationtimeofflight spectroscopy of cold perfluorinated polyethers and their external and internal van ...
applications to the Human Genome Project
Chapter 19 Factors affecting the resolution in matrixassisted laserdesorptionionization mass spectrometry
evaluation of postsource decay following matrixassisted laser desorption ionisation MALDI
Chapter 21 Energyisochronous timeofflight mass analyzers
a new dimension in single iontimeofflight mass spectrometry
structuralinformation for a mass spectrum and mass informationfor ionic spectroscopy
Chapter 11 Decay energetics of molecular clusters studied bymultiphoton mass spectrometry and pulsed fieldthreshold ionization
Chapter 12 Using reflectron timeofflight mass spectrometer techniques to investigate cluster dynamics and bonding
intramolecular clocking ofenergy redistribution for molecules falling apartl