Total Synthesis of Natural Products: At the Frontiers of Organic Chemistry

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Jie Jack Li, E.J. Corey
Springer Science & Business Media, Mar 14, 2013 - Science - 279 pages
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'Total Synthesis of Natural Products' is written and edited by some of today's leaders in organic chemistry. Eleven chapters cover a range of natural products, from steroids to alkaloids. Each chapter contains an introduction to the natural product in question, descriptions of its biological and pharmacological properties and outlines of total synthesis procedures already carried out. Particular emphasis is placed on novel methodologies developed by the respective authors and their research groups. This text is ideal for graduate and advanced undergraduate students, as well as organic chemists in academia and industry.

 

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Contents

Chapter 1 Nominine
1
Chapter 2 Nakiterpiosin
25
Chapter 3 The Kinamycins
39
Chapter 4 A Short Synthesis of Strychnine from Pyridine
66
Chapter 5 Bryostatin 7
103
Chapter 6 Serratezomine A
131
Chapter 7 HypocrellinCercosporin
157
Chapter 8 Phomactin A
183
Chapter 9 +1111Dideoxyverticillin A
211
Chapter 10 Retigeranic acid
234
Chapter 11 Total Synthesis of the Lycopodium Alkaloid Complanadine A
259
Index
273
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About the author (2013)

JIE JACK LI is a medicinal chemist at Pf izer Global Research and Development in Ann Arbor, Michigan. His research interests include medicinal chemistry, heterocyclic chemistry, transition metal-catalyzed reactions, and radical chemistry. He is author of "Name Reactions: A Collection of Detailed Reaction Mechanisms," and coauthor of "Palladium in Heterocyclic Chemistry and Contemporary Drug Synthesis," also published by Wiley.

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