Toxicological profile for benzidine: draft
United States. Agency for Toxic Substances and Disease Registry, Life Systems, Inc, Clement International Corporation
Agency for Toxic Substances and Disease Registry, 1993 - Medical - 121 pages
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3,3'-dichlorobenzidine absorption acetylated aromatic amines arylamines assay assessment ATSDR azo dyes benzidine-based dyes benzidine's bile bioactivation biomarker bladder cancer Carcinogenesis carcinogenic chemical compounds concentration cytochrome P-450 data No data derivatives dermal exposure detected determination of benzidine DNA adduct DNA repair dogs dose effects in humans effects of benzidine end points Environ Health Environmental Protection Agency epidemiological evaluation excretion exposure to benzidine Forward mutation genotoxicity glucuronide health effects hepatic hepatocytes humans or animals induced inhalation exposure Lakshmi liver LOAEL located regarding LSE tables metabolites mg/kg/day mg/L mice microsomes mutagenicity Mutat Res mutation Reverse mutation natural killer cell NIOSH NOAEL occupational exposure oral exposure oxidation potential prostaglandin prostaglandin H synthase Rat S-9 Rat reported Reverse mutation Reverse risk route of exposure Sciarini and Meigs significant soil species studies were located substance tissue Toxicol toxicological tumors typhimurium U.S. Environmental Protection urinary urinary bladder urine vitro vivo workers exposed