Translational Research and Clinical Practice: Basic Tools for Medical Decision Making and Self-Learning

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Oxford University Press, USA, Nov 17, 2010 - Medical - 137 pages
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Translational Research and Clinical Practice offers a clear and comprehensive introduction to evidence-based medicine. The use of medical literature has always been an integral tool for patient care, yet recently the modern processes of question formulation, literature search, and study evaluation have changed with the advent of the internet and technology. The physician must be able to find empirical evidence from the appropriate study using a searchable question and then determine its impact on patient care. The book provides the general framework for such medical decision making; it covers all kinds of cases and strategies, including questions of diagnosis, therapy, prognosis, differential diagnosis, clinical presentation, and causality.The tested material and approaches in this book are based on a course developed and taught by the author at Temple University School of Medicine. Organized for ease of use, accessibly written, and replete with clinically germane examples, Translational Research and Clinical Practice is a concise guide for medical students and clinicians seeking to effectively interpret and apply medical evidence in daily practice.
 

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Contents

1 Developing a Clinical Question and Searching the Medical Literature
3
2 The Anatomy of a Clinical Study
7
3 Designs of Clinical Studies
15
4 Lies More Lies and Statistics With Apologies to Mark Twain
21
5 Answering a Question Regarding the Treatment of a Disease
31
6 Answering a Question Regarding the Utility of a Diagnostic Test
39
7 Answering a Question Regarding Prognosis and Risk Factors
49
8 Answering a Question Using a Clinical Prediction Rule
55
10 Using Medical Evidence to Answer a Question Regarding Clinical Presentation
67
11 Using MetaAnalyses to Answer a Question of Diagnosis and Therapy
73
12 Answering a Question Regarding Causation
83
Prepackaged Medical Decision Making
89
14 Putting It All Together
95
15 Developing a Plan for Lifelong Education
121
16 Teaching Medical Decision Making
127
Index
133

9 Answering a Question about Etiology or Differential Diagnosis
63

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About the author (2010)


Waldo E. Nelson Professor and Chair, Department of Pediatrics, Temple University School of Medicine, Philadelphia, Pennsylvania

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