Vascular Manifestations of Systemic Autoimmune Diseases
Ronald A. Asherson, Ricard Cervera, Douglas A. Triplett, Steven B. Abramson
CRC Press, Jan 25, 2001 - Medical - 624 pages
Not too long ago, it was thought that inflammation of blood vessels was the sole manifestation of systemic autoimmune diseases. Today, however, we know that disorders of coagulation, injuries to both neutrophils and endothelial cells, and certain lipids and amino acids are all intricately involved in the development of vascular disease. How are all these processes linked? What strategies can we employ or develop to halt the progression of vascular damage? What are the best ways to control acute vasculitis and vasospasm therapeutically? What are the risks and benefits of various strategies for the prevention of clotting? How soon should we initiate preventive strategies that protect blood vessels from arteriosclerosis in people with acute rheumatic diseases? What should be the nature of those strategies?
Vascular Manifestations of Systemic Autoimmune Diseases provides answers to all these questions. Ronald Asherson, Richard Cervera,Steven B. Abramson, Jean-Charles Piette, and Douglas Triplett- all international experts in the field-have assembled a collection of works that provide a comprehensive analysis of vascular irregularities. Now that most individuals survive the onset of acute systemic autoimmune diseases and live for decades more, halting the long-term attack on vasculature is increasingly important.
Vascular Manifestations of Systemic Autoimmune Diseases not only describes the clinical symptoms of vascular diseases; it also covers in one volume the many mechanisms involved in the pathogenesis of these disorders and addresses the newest treatments available for them.
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acute adhesion molecules AECA ANCA aneurysms antigen antiphospholipid antibodies antiphospholipid syndrome aortic Arthritis Rheum aspirin associated atherosclerosis autoantibodies autoimmune Behçet’s disease biopsy blood chronic circulating Clin clinical coronary artery cryoglobulinemia cryoglobulins cutaneous cytokines diagnosis disease activity dose effects endothelial cells endothelium estrogen factor glomerular glomerulonephritis Henoch-Schonlein purpura heparin hepatitis homocysteine hormone immune complexes Immunol increased induced infarction infection infiltration inflammation inflammatory inhibition Journal Kawasaki disease kidney lesions levels lupus anticoagulant manifestations membrane myocardial necrosis necrotizing neutrophils occlusion oral oxide pathogenesis patients with systemic Pediatrics plasma platelet polyarteritis nodosa present protein pulmonary hypertension Raynaud’s phenomenon receptor relapse renal involvement reported Rheumatism rheumatoid Rheumatol Rheumatology risk role scleroderma serum Sjögren’s syndrome skin smooth muscle steroids systemic lupus erythematosus systemic sclerosis systemic vasculitis Takayasu arteritis Takayasu’s arteritis therapy Thromb thrombocytopenia thrombosis thrombotic tissue treatment vascular vasculitic vasculitides venous vessels warfarin Wegener’s granulomatosis