Vitamin History, the Early Years

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First Edition Design Pub., Feb 11, 2013 - Health & Fitness - 290 pages
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Casimer Funk 101 years ago first used the term "vitamine" in 1912. What were later to be known as vitamin-deficiency diseases, such as scurvy, beriberi, night blindness, xerophthalmia and rickets, had plagued the world at least since the existence of written records. Records of medical science from antiquity attesting to human association of certain foods(e.g. liver) with either the cause or prevention of diseases are considered the nebulious beginnings of the concept of these essential nutrients. The concept of a vitamin or "accessory growth factor" was developed in the early part of the 20th Century and for almost five decades there was an exciting era of isolation, identification and synthesis of the vitamins. The present book contains 10 chapters and methodically traces each vitamin from an unidentified factor to its discovery and synthesis. In relation to history of nutrition, vitamins are by far the most interesting class of nutrients. Following the clues of the existence of each vitamin is similar to a good mystery story. The early beginnings of the vitamin theory relate to reports that animals did not survive on diets of only carbohydrares, fats, protein and salts. Beriberi was the earliest documented deficiency disorder (2697 B.C.). High incidence of beriberi in Asian countries was due to over milling rice( polished rice). The subsequent research in this disease led to the discovery of vitamins and helped to establish some of the principal features of deficiencies in general. Vitamin A deficiency results the in two eye diseases of night blindness and xeropthalmia. According to some of the oldest records, liver cured these diseases. Rickets, the devastating bone disease of young children is a vitamin D deficiency. The vitamin is referred to as the "sunshine vitamin" as it can be synthesized in the body. Rickets was common in northern cities and was more rampant in industrial cities as industrial pollution prevented children from sunlight exposure. Pellagra, a niacin deficiency, is a devastating disease that brought pain, suffering and death and resulted when corn was the main food source. Symptoms of the disease were referred to as the 4 D's, dermatitus, diarrhea, dementia and death. Scurvy which had been feared since ancient times resulted from diets devoid of vitamin C-rich foods of fruits and vegetables. Scurvy was the vitamin deficiency disease that caused the most death and suffering in recorded history. A fatal anemia, pernicious anemia, was a vitamin B-12 deficiency. The disease resulted by only consuming plant foods, or lack of a factor produced by the stomach needed for absorption of the vitamin. The book contains pictures of very serious consequences and magnitude of vitamin deficiency diseases. Likewise, the book contains levity by illustrating humorous situations on causes and cures of these diseases. The purpose of the present publication is to present an in depth review of the early history of vitamins to illustrate the devastation of these diseases and also provide some levity. Author Bio: The author of the book, Dr. Lee McDowell is a nutritional professor at the University of Florida. In nutrition research he has published over 1500 scientific articles and has written 7 books. Five different nutrition courses have been taught, with a graduate vitamin nutrition course offered over 25 years. During this time period he wrote two editions of a vitamins textbook for his graduate class and for courses at other universities. Dr McDowell is a "Fellow" of two International Societies and has won many awards in teaching and research. From one society he won the highest award available for research (Morrison Award). Internationally Dr. McDowell is well known having made 271 different country visits since 1971. He has given over 500 major talks in 42 different countries. "Early Vitamin History," presented in a humorous way, is his most favorite topic.
 

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Regarding infantile beri-beri, this book provides extremely valuable information connection polished rice, and the lack of access to nutritious brown rice, and the spread of the disease from breastfeeding mother to newborns. The work of Dr. Manuel Guerrero, and his contribution to finding the cure for the disease, is important. Thank you. 

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Contents

IN THE BEGINNING HISTORY OF VITAMINS I Introduction
Ancient Diseases Related to Diet
Biochemical And Analytical Advances IV Deficiency Diseases Using Purified Diets And Animals
Summary
References
BERIBERI I Introduction II What Is The Cause Of Beriberi?
Early Theories On Causes Of Beriberi
Beriberi In Various Geographical Locations
Summary
References
VITAMIN E I Introduction
Vitamin E And Affects Of Deficiency? III History
Deficiency Today And Supplementation Considerations
Summary
References
VITAMIN K I Introduction II Vitamin K Deficiency

Beriberi As A Nutritional Deficiency
Beriberi Preventions And Cures
Beriberi Today
Summary
References
XEROPHTHALMIA AND NIGHT BLINDNESS I Introduction II What Is The Cause Of Xerophthalmia And Night Blindness?
Clinical Signs And Symptoms Of Xerophthalmia And Night Blindness
Xeropthalmia And Night Blindness History From Antiquity To 14th Century V Xeropthalmia And Night Blindness History 13001900
Relationship Of Cod Liver Oil To Eye Disease VII Vitamin A History In 1900 s Discovery And The Vitamin Theory
Vitamin A Deficiency Today
Vitamin A Toxicity
Summary
References
RICKETS I Introduction II What Is The Cause Of Rickets?
Clinical Signs And Symptoms Of Rickets
Rickets History From Antiquity To The 17th Century
Rickets History From The 17th To 20th Century
Rickets History In The 20th Century
Vitamin D Deficiency Today
Summary
References
DEFICIENCIES OF THE BVITAMINS RIBOFLAVIN VITAMIN B6 PANTOTHENIC ACID BIOTIN AND FOLACIN I Introduction II Riboflavin
Vitamin
Pantothenic Acid
Biotin
Folacin
History
Deficiency Today And Supplementation Considerations
Summary
References
PELLAGRA I Introduction II What Is The Cause Of Pellagra? III Clinical Signs And Symptoms Of Pellagra
Pellagra Was Associated With High Levels Of Corn Consumption
Pellagra History In Europe And The Eastern Hemisphere
Pellagra History In North America
Incidence Of Pellagra Late l730sl952 VIII Theories On Cause Of Pellagra IX Determination Of Pellagra As Nutritional Deficiency X Pellagra Treatm...
Pellagra Today
Summary
References
SCURVY I Introduction II What Is The Cause Of Scurvy? III Clinical Signs And Symptoms Of Scurvy
Early Ideas For Cause Prevention And Cure Of Scurvy
History Of Scurvy From Antiquity To 1440s
History Of Scurvy From 1440s To Mid 19005
Discovery Of Vitamin C
Summary
References
PERNICIOUS ANEMIA I Introduction II What Is The Cause Of Pernicious Anemia?
Characteristics And Symptoms Of Pernicious Anemia
History Of Pernicious Anemia
Vitamin B12 Deficiency Today And B12 Supplementation
Summary
References About the Author

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