Water and Biological Macromolecules
Taylor & Francis, Aug 16, 1993 - Science - 466 pages
Water and Biological Macromolecules presents an excellent description of the structural aspects of water molecules around biological macromolecules. Topics discussed include the properties of water in solid and liquid states; proteins, nucleic acids, polysaccharides, and lipids; and theoretical approaches for understanding the macroscopic observations and integrating microscopic descriptions. The nature and roles of hydration forces in macromolecular complexation and cell-cell interactions are explained, in addition to phenomena such as entropy-enthalpy compensation and the thermodynamic treatment of water bridging.
Water and Biological Macromolecules will be a valuable reference for biophysicists, biochemists, and macromolecular biologists.
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Thermodynamic and dynamic properties of water
Hydration of amino acids in protein crystals
20 other sections not shown
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8-sheet analysis anionic aqueous atoms B-DNA B-form backbone base pairs Ben-Naim Beveridge Biochemistry Biochim Biol Biophys biopolymers calculations cell Cevc chain Chem Clementi complex conformation correlation counterions crystal structure crystalline crystallographic d(CGCGAATTCGCG density dielectric distance dodecamer effects electron electrostatic Equation experimental Figure force field free energy function Goodfellow H-bond helix Helmholtz energy hydration hydration forces hydration shell hydrogen bonds hydrophilic hydrophobic interactions interfacial ions kcal/mol layer lipid bilayers lipid headgroups liquid macromolecules MD simulation membrane minor groove molecular dynamics Molecular dynamics simulation Monte Carlo neutron diffraction nucleic acids nucleotide orientation oxygen parameters phase transition phosphate groups phosphatidylcholine phospholipid Phys polar polymer polysaccharides potential protein refinement relaxation repulsion residues resolution side-chains solubility solution solvation Gibbs energy solvent solvent molecules solvent structure stability studies surface temperature thermodynamic tion water bridges water molecules water structure Westhof X-ray Z-DNA