WHO Expert Committee on Drug Dependence: Thirty-third Report, Volume 33
World Health Organization, 2003 - Health & Fitness - 26 pages
This report presents the recommendations of a WHO Expert Committee responsible for reviewing information on dependence-producing drugs to assess the need for their international control. The first part of the report contains a description of the procedure for the review of dependence-producing substances. This is followed by a critical review of five psychoactive substances (amfepramone amineptine buprenorphine delta-9-tetrahydrocannabinol and tramadol). The report also discusses the substances that were pre-reviewed by the Committee four of which (ketamine zopiclone butorphanol and khat) were recommended for critical review at a future meeting. The final section discusses the problems of the terminology used in reporting abuse-related adverse drug reactions and describes how confusion affects the reporting of adverse effects using the example of the selective serotonin reuptake inhibitors.
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1971 Convention abuse and/or evidence abuse liability abuse potential Actual abuse and/or adverse drug reaction amfepramone amineptine analgesic anorectic antidepressant buprenorphine butorphanol cannabis central nervous system codeine Committee considered Committee on Drug Committee recommended delta-9-tetrahydrocannabinol Dependence potential dependence syndrome diagnostic guidelines diversion and abuse dronabinol drug abuse drug dependence drug maladministration drug monitoring programme ECDD Essential Drugs evidence of likelihood Expert Committee INCB international control international drug monitoring Ketamine khat liability to abuse likelihood of abuse marketed Medicines Policy morphine narcotic drugs number of reports opioid dependence oripavine paroxetine patients pentazocine pharmacological pre-reviewed psychoactive substances psychotropic substances pu-opioid receptor public health review of psychoactive risk to public Schedule IV scheduling criteria significant Similarity to known SSRIs stimulants Substance identification substances and effects substances for international Substances whose liability Switzerland Technical Report Series thebaine therapeutic tramadol United Nations Uppsala Monitoring Centre withdrawal syndrome World Health Organization Zaleplon zopiclone