Women’s Health and Menopause: Risk Reduction Strategies — Improved Quality of Health

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Rodolfo Paoletti, P.G. Crosignani, P. Kenemans, N.K. Wenger, Ann S. Jackson
Springer Science & Business Media, Jul 11, 2007 - Medical - 291 pages
The population structure in the world is rapidly changing, to the extent that in 75 years we will face a tripling of the elderly population. Although women are favored in terms of life expectancy, they also live with a longer period of disability (approximately twice that of aging men), as well as with the enemies of all the elderly, cardiovascular disease, cancer, and dementia. Menopause is the endocrine event that overlaps with aging, potentially worsening both the quality of life and the risks of disease in women.While the effect of hormone replacement therapy (HRT) on menopausal symptoms is generally viewed as rapid and consistent, and is thereby accepted by the scientific community, its relationship to the other aforementioned chronic conditions associated with menopause is considered variable and controversial.In analyzing these complex issues, this volume yields new and significant insights into both the study of menopause-related disorders and their treatment, by illustrating the most recent information on mechanisms of actions of new estrogen receptors and on the use of sophisticated techniques of statistical analysis for population-based studies.
 

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Contents

Chronic LowGrade Metabolic Acidosis in Normal Adult 15
14
ESTROGENPROGESTOGEN ACTION
32
Nongenomic Mechanisms of Sex Hormones
47
Newer Progestogens
67
Risk Factors Related to Thrombosis
75
12 Estrogen Effect upon Coronary Vasculature
83
Estrogen and Endothelial Function
89
Effects on
99
Hypotheses on the Biological
151
The American 1 65
165
Once a Week Transdermal EstrogenQuality of Life Improvement in
183
Selective Estrogen Receptor Modulator SERM Drugs for the
199
Breast and Female Genital Tract Neoplasms in Overweight Women 217
216
Postmenopausal Hormone Replacement Therapy and Gynecological
225
Hormone Replacement Therapy and Breast Cancer Risk in HighRisk 233
232
Breast Cancer and HRT Collaborative Reanalysis of Data
243

Status 1998
105
Genetics of Osteoporosis
117
The Clinical Management of Osteoporosis
125
CENTRAL NERVOUS SYSTEM
131
Target and Source for Sex Steroid Hormones
137
The Role of Estrogen in Brain Aging and Alzheimers Disease 145
144
A Summary of the Evidence Relating Postmenopausal Hormone Use
249
EPIDEMIOLOGICALSTUDIES ANDMEDICAL PERCEPTION
256
The ICARUS Italian Climacteric Research Group Study
267
Sciacchitano for the ICARUS Osteoporosis Study Subgroup
275
A View from the Italian Menopause
285
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