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A Model for Therapeutic Interventions on Established
The Nonhuman Primates as Models for Studying Human
Phylogenetic Variability of Serum Lipids and Lipoproteins
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7-ketocholesterol activity animals aorta aortic apolipoproteins arterial wall athero atherogenesis atherogenic atherogenic diet Atheroscler atherosclerosis atherosclerotic lesions baboon Biochem Biol blood CBA/j chimpanzee choles cholesterol concentration cholesterol diet cholesterol synthesis Clin CM CM coronary arteries decrease desmosterol diabetic dietary cholesterol dose drugs effect experimental atherosclerosis fatty streaks Figure foam cells fraction HC VLDL HC+Met HDL2 high density lipoproteins high-cholesterol diet hypercholesterolemia hyperlipoproteinemia increased inhibition injected intimal thickening Japanese quail lipid lipid inclusions liver low density lipoproteins male rats mean serum total membrane mg/dl mice normal Pathol phospholipids plaque plasma plasma lipoproteins Poor Responder protein rabbits radioactivity regression response rhesus monkeys serum cholesterol levels serum lipids serum lipoproteins serum total cholesterol significantly smooth muscle cells species sterol sterol synthesis strain studies Table tissue total cholesterol levels triglycerides uptake vascular vitro VLDL weeks