Molecular Targets and Therapeutic Uses of Spices: Modern Uses for Ancient Medicine
World Scientific, 2009 - Technology & Engineering - 430 pages
Most therapeutics available today are highly toxic, very expensive and exhibit minimum efficacy. The issue of toxicity is even more critical for prevention than for therapy because the former involves normal subjects. Thus, therapeutics that are safe and affordable are needed for both prevention and therapy. Spices of Southeast Asian origin, once employed for taste, appearance and preservation of food, now appear to have therapeutic value for humans. What the active principles in these spices are and how they mediate their effect against various diseases are beginning to emerge from extensive research carried out within the last half-century. The current monograph is an attempt to address the active constituents, their molecular targets and the therapeutic uses of these spices.
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Chapter 2 Black Pepper Piper nigrum and Its Bioactive Compound Piperine
Chapter 3 Cardamom Elettaria cardamomum and Its Active Constituent 18cineole
Chapter 4 Molecular Targets and Health Benefits of Cinnamon
Chapter 5 Cloves Eugenol
Chapter 6 Coriander
Chapter 7 Fenugreek Diosgenin
Chapter 8 Diallyl Sulfide from Garlic
Chapter 9 Ginger 6gingerol
Other editions - View all
6]-gingerol activity agents angiogenesis anti-inflammatory anticancer antioxidant apoptosis apoptotic aqueous extract bark Biochem Biol black pepper Ca2+ cancer cells capsaicin carcinogen carcinogenesis carcinoma cardamom caspase-3 CCR3 cell cycle cell lines Chem chemical chemopreventive cinnamon clinical colon compounds constituents coriander curcumin cyclin cytochrome cytotoxicity decreased demonstrated diabetes dietary diosgenin diseases dose downregulation drugs effect of piperine enhanced enzymes essential oils eugenol eugenol-related expression fenugreek Food Garcinia Garcinol Inhibits garlic gastric gene ginger glucose glutathione herbal human increased induces apoptosis inflammation inflammatory inhibitor insulin intestinal isoeugenol kinase kokum levels lipid peroxidation liver lung mechanisms mediated medicine Mentha metabolism mg/kg mice modulation molecular targets mouse Nigella sativa oral oxidative pathways patients Pharmacol phenolic phosphorylation piperine plant potential proliferation protein radical rats receptor reduced role RosA rosmarinic acid seeds shown signaling significantly skin spices stimulation studies suppression therapeutic thymoquinone toxicity Toxicol treatment tumor vitro vivo