Liver and Aging, 1990: Proceedings of the Fourth Tokyo Symposium on Liver and Aging, Held in Tokyo, Japan, on August 15-17, 1990Kenʼichi Kitani Based on the fourth symposium on liver and aging, this book has two main topics: the detoxifying systems in the liver, and the role of liver proteins in aging processes. All the chapters in this volume have significant implications as well as future potential for understanding the fundamental mechanisms of cellular aging and for promoting the well-being of the elderly. Collaboration between different researchers and laboratories is urgently needed to enhance the progress of research in this field. This book testifies to collaborative efforts by several different laboratories, and points the way to further development of additional collaborative research projects in this most challenging field. |
Contents
The effects | 17 |
DRUG METABOLISM 2 RODENTS VS PRIMATES | 33 |
The influence of frailty liver blood flow and size upon hepatic oxidation | 45 |
Copyright | |
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Common terms and phrases
accumulation acute phase age-related aged rats albumin altered antibody B-muricholic acid bile acid Biochem Biol Biophys bromperidol ceroid changes cholesterol cholic acid clearance concentration cytochrome P-450 decline decrease diet dietary restriction dose drug metabolism effect of age elderly endotoxin enzyme enzyme activities ethanol expression female rats fluorescent fraction Fujita function gene Gerontol glutathione heat shock hepatic hepatocytes hepatotoxicity increase induction inhibited intracellular isolated isosafrole isozyme Kenichi Kitani Kupffer cells leupeptin libitum lipid lipofuscin liver Liver and Aging liver microsomes lysosomal male rat liver measured mice microsomal monooxygenase months morbidity mRNA mRNA levels neuroleptic level normal observed old animals old patients old rats ouabain oxidative paracetamol Pharmacol pigment plasma membrane protein receptor reductase response Rikans senescence serum shown significant significantly specific studies substrates subunit T-kininogen tissue toxic uptake values vitro vivo young and old young rats Zs.-Nagy