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activity addition AIDS analysis animals antigen assay associated Bethesda binding Biology blood blot CD4+ cell culture cell lines Center clinical clones compared concentrations containing culture demonstrated described detected determined dilution disease drug Duke University effect enhancer envelope epitope experiments expression factors function Gallo gene HIV infection HTLV-I human immunodeficiency virus immune increase incubated indicate individuals induced inhibition Institute interaction isolates Italy Laboratory levels lymphocytes Medical medium Methods Molecular molecule monkeys monoclonal antibodies National Cancer Institute Nature neutralizing normal observed obtained patients peptide population positive present production progression protein purified reactivity receptor recombinant region replication reported Research response retrovirus samples sequence sera seropositive serum showed shown significant specific stimulation studies subjects suggest syncytia T-cell Table tested titers treatment Tumor University vaccine viral viruses vitro Western blot