Developmental Biology, Volume 3
Publishing in May 2013, Scott Gilbert's Developmental Biology, Tenth Edition embodies the breadth, the intellectual rigor, and the wonder of contemporary developmental biology. Written primarily for undergraduate biology majors, this book can also serve to introduce graduate students and medical students to the field. The completely updated text integrates classical developmental biology with all the incredible advances that have been made in recent years. Dr. Gilbert's unique ability to synthesize the breakthroughs in this rapidly evolving discipline in a succinct, organized manner has made Developmental Biology the go-to source for a generation of teachers and nascent developmental biologists. New: * "Integration" has emerged as the key theme in developmental biology over the past three years. The mechanisms of transcriptional gene regulation and of aging, the data on amniote limb development, the ways in which fertilization occurs, and the mechanisms of sex determination-each has been integrated. Even developmentally important genes have been "integrated" into genetic regulatory networks. The new Tenth Edition reflects this exciting new age of genomics, genetic regulatory networks, and digital visualization techniques. * Cytoskeletal dynamics, which integrate the genetic regulatory genes with morphogenetic events, has overhauled the discussions of neural development and cell signaling. Enduring Features: * An evolutionary context, provided in the first chapter and continued throughout the book, now incorporates the revolutionary new discoveries of the horizontal transfer of enhancer-bearing transposable elements as well as the possible origins of multicellularity as a developmental response to bacteria. * The book maintains its four-part structure with brief part openers that address key concerns in developmental biology and provide an introduction to the subsequent chapters. Each chapter ends with a guide to Web-based resources r
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PART ONE m QUESTIONS Introducing Developmental Biology
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3-catenin acrosome activate adult amphibian animal anterior-posterior axis axons become Bicoid bind blastocoel blastomeres blood bone brain cartilage cell division cell membrane cell types cells migrate chick embryo chromosome cleavage courtesy cytoplasm developmental differentiation dorsal Drosophila ectoderm embryo encoding endoderm enhancer enzymes epiblast epidermis exons extracellular female fertilization Fgf8 FIGURE formation frog function gastrulation gene expression genetic germ cells gonads gradient growth hedgehog histone hormone human induce inhibits interactions larva layer male mammalian mammals meiosis mesenchyme cells mesoderm methylation mice micromeres mouse mRNA muscle mutations neural crest cells neural tube neurons notochord nucleosomes nucleus oocyte organs paracrine paracrine factors pathway pattern Pax6 posterior precursors produce promoter protein receptor region regulate sclerotome sea urchin sequence signal somite Sonic hedgehog specific sperm splicing stage stained stem cells synthesis tion tissue transcription factors vegetal ventral vertebrate vesicle WEBSITE Xenopus yolk zebrafish