Islet Transplantation in the Treatment of Diabetes: Number of Islets, Functional Regulation and Metabolic Control |
From inside the book
Results 1-3 of 81
Page 34
... diabetic rats was abnormal ( Müller et al . 1970 ) . Moreover , the glucagon response to arginine infusion in islet transplanted rats at three days after transplantation exceeded that in diabetic and healthy control rats . This high ...
... diabetic rats was abnormal ( Müller et al . 1970 ) . Moreover , the glucagon response to arginine infusion in islet transplanted rats at three days after transplantation exceeded that in diabetic and healthy control rats . This high ...
Page 12
... diabetic condition under experimental conditions in the rat , whereas islets from several donors were needed without insulin treatment ( 7 , 8 ) . Similarly , strict metabolic control of diabetic rats decreased the number of neonatal ...
... diabetic condition under experimental conditions in the rat , whereas islets from several donors were needed without insulin treatment ( 7 , 8 ) . Similarly , strict metabolic control of diabetic rats decreased the number of neonatal ...
Page 17
... diabetic control rats showed marked hyperglycemia compared with the controls ( P < 0.001 ) . Also streptozotocin - diabetic rats treated with insulin from day 1 after diabetes induction to day 7 remained hyperglycemic after 3 months ...
... diabetic control rats showed marked hyperglycemia compared with the controls ( P < 0.001 ) . Also streptozotocin - diabetic rats treated with insulin from day 1 after diabetes induction to day 7 remained hyperglycemic after 3 months ...
Contents
1 Introduction | 7 |
2 Aim of the study | 24 |
5 General discussion | 47 |
Copyright | |
1 other sections not shown
Common terms and phrases
Ahrén animals B-cells blood glucose levels cells Clin clinical collected complications contrast control rats cyclosporine days after diabetes days after transplantation determined developed diabetes induction diabetes mellitus diabetic control diabetic rats Diabetologia diffusion chambers donor dose level effect et al experimental Figure function Furthermore given glucagon glucagon secretion glucose infusion Gray healthy control hyperglycemia importance improved increased injection insulin response insulin secretion insulin treatment irradiation islet graft islet transplantation islets of Langerhans isolated kidney Lacy late light long-term lower Means mechanism method mg/kg minutes months normal normoglycemia pancreatic islets panel performed period plasma glucose levels plasma insulin levels prevent previously rats transplanted reduced regulation rejection remained renal subcapsular space reported response to glucose restore short-term showed shown Sprague-Dawley rats stimulation strains streptozotocin streptozotocin administration streptozotocin-diabetic rats successful sufficient suggested tissue transplanted islets transplanted rats transplanted with 400 treated yohimbine