Islet Transplantation in the Treatment of Diabetes: Number of Islets, Functional Regulation and Metabolic Control |
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Page 16
... Glucose infusion ( Figures 2 and 3 ) At 10 days after transplantation , i.e. , at day 12 after diabetes induction , the increase in plasma insulin levels during IV glucose infusion in rats transplanted with 400 islets was significantly ...
... Glucose infusion ( Figures 2 and 3 ) At 10 days after transplantation , i.e. , at day 12 after diabetes induction , the increase in plasma insulin levels during IV glucose infusion in rats transplanted with 400 islets was significantly ...
Page 6
... Glucose infusion Intravenous glucose infusion was performed at 10 days ( Figures 3 and 4 ) or at 6 months ( Figure 5 ) after transplantation . Rats transplanted with 1500 non - immunoisolated islets had a plasma insulin response not ...
... Glucose infusion Intravenous glucose infusion was performed at 10 days ( Figures 3 and 4 ) or at 6 months ( Figure 5 ) after transplantation . Rats transplanted with 1500 non - immunoisolated islets had a plasma insulin response not ...
Page 4
... glucose levels , to 232 mM ( P < 0.05 ) , whereas yohimbine had no effect on basal plasma glucose levels in the ... infusion ( 10 mg / min ) at 3 months after transplantation of 1000 islets into the renal subcapsular space in streptozotocin - ...
... glucose levels , to 232 mM ( P < 0.05 ) , whereas yohimbine had no effect on basal plasma glucose levels in the ... infusion ( 10 mg / min ) at 3 months after transplantation of 1000 islets into the renal subcapsular space in streptozotocin - ...
Contents
1 Introduction | 7 |
2 Aim of the study | 24 |
5 General discussion | 47 |
Copyright | |
1 other sections not shown
Common terms and phrases
Ahrén animals B-cells blood glucose levels cells Clin clinical collected complications contrast control rats cyclosporine days after diabetes days after transplantation determined developed diabetes induction diabetes mellitus diabetic control diabetic rats Diabetologia diffusion chambers donor dose level effect et al experimental Figure function Furthermore given glucagon glucagon secretion glucose infusion Gray healthy control hyperglycemia importance improved increased injection insulin response insulin secretion insulin treatment irradiation islet graft islet transplantation islets of Langerhans isolated kidney Lacy late light long-term lower Means mechanism method mg/kg minutes months normal normoglycemia pancreatic islets panel performed period plasma glucose levels plasma insulin levels prevent previously rats transplanted reduced regulation rejection remained renal subcapsular space reported response to glucose restore short-term showed shown Sprague-Dawley rats stimulation strains streptozotocin streptozotocin administration streptozotocin-diabetic rats successful sufficient suggested tissue transplanted islets transplanted rats transplanted with 400 treated yohimbine