Islet Transplantation in the Treatment of Diabetes: Number of Islets, Functional Regulation and Metabolic Control |
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Page 22
... islet function ( Andersson et al . 1984 ; Basadonna et al . 1988 ) . Therefore , using smaller dose of cyclosporine ... islet graft and short - term cyclosporine treatment ( Hardy et al . 1984 ) or induction of immunosuppression with ...
... islet function ( Andersson et al . 1984 ; Basadonna et al . 1988 ) . Therefore , using smaller dose of cyclosporine ... islet graft and short - term cyclosporine treatment ( Hardy et al . 1984 ) or induction of immunosuppression with ...
Page 38
... islet function after transplantation are of great importance since this could allow the use of a smaller number of islets . Furthermore , if the islets from only one donor were sufficient , the same donor may be used for combined kidney and ...
... islet function after transplantation are of great importance since this could allow the use of a smaller number of islets . Furthermore , if the islets from only one donor were sufficient , the same donor may be used for combined kidney and ...
Page 48
Number of Islets, Functional Regulation and Metabolic Control Aamer Ar'Rajab. the reason for the long - term survival also of the syngeneic outbred islets . For example , it has been shown that the use of pure islets prolongs the survival ...
Number of Islets, Functional Regulation and Metabolic Control Aamer Ar'Rajab. the reason for the long - term survival also of the syngeneic outbred islets . For example , it has been shown that the use of pure islets prolongs the survival ...
Contents
1 Introduction | 7 |
2 Aim of the study | 24 |
5 General discussion | 47 |
Copyright | |
1 other sections not shown
Common terms and phrases
Ahrén animals B-cells blood glucose levels cells Clin clinical collected complications contrast control rats cyclosporine days after diabetes days after transplantation determined developed diabetes induction diabetes mellitus diabetic control diabetic rats Diabetologia diffusion chambers donor dose level effect et al experimental Figure function Furthermore given glucagon glucagon secretion glucose infusion Gray healthy control hyperglycemia importance improved increased injection insulin response insulin secretion insulin treatment irradiation islet graft islet transplantation islets of Langerhans isolated kidney Lacy late light long-term lower Means mechanism method mg/kg minutes months normal normoglycemia pancreatic islets panel performed period plasma glucose levels plasma insulin levels prevent previously rats transplanted reduced regulation rejection remained renal subcapsular space reported response to glucose restore short-term showed shown Sprague-Dawley rats stimulation strains streptozotocin streptozotocin administration streptozotocin-diabetic rats successful sufficient suggested tissue transplanted islets transplanted rats transplanted with 400 treated yohimbine