The Scientific Basis of Modern Radiotherapy: An International Symposium to Mark the Achievements of John Francis Fowler After 18 Years as Director of the Gray Laboratory (October 1969-March 1988) Held in the Fowler-Scott Library of the Cancer Research Campaign Gray Laboratory, Northwood, Middlesex, 30th June-2nd July 1988Nicolas J. McNally This volume reviews key areas of radiotherapy, examining the scientific basis in relation to clinical practice. It represents the proceedings of a conference held to mark the achievements of John Fowler and includes contributions from leading figures from Europe and the USA. |
Contents
Some considerations of repair in the design of multiplefractionsperday treatment schedules | 5 |
Variation in aẞ based on available time for repair | 17 |
Biology of options in dose fractionation | 27 |
Copyright | |
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accelerated agents analysis applied Biology blood flow British Journal Cancer carcinoma cause changes clinical clonogen combined compared course curves damage decreases Denekamp dependence developed dose per fraction doubling drug early effect Equation estimated et al evidence experimental experiments factors field Figure Fowler function give given Gray growth heat human tumours hyperthermia hypoxic increase indicate influence International Journal irradiation Journal of Radiation kinetics labelled Laboratory late lesions lethal linear lung measured method mouse neutrons normal tissues obtained oxygen patients period Physics points possible potential proliferation protection Radiation Oncology Radiation Research radiosensitivity radiotherapy range ratio rays reduced relative repair repopulation Research response sensitivity shown shows single skin studies suggested Table technique temperature term Thames therapeutic therapy tion tolerance total dose treated treatment trial tumour cells values vascular vessels volume weeks WITHERS