Goodman & Gilman's the Pharmacological Basis of Therapeutics
McGraw-Hill, Health Professions Division, 1996 - Chemotherapy - 1905 pages
For more than 50 years, scientists, clinicians and students have relied on this reference for information on the pharmacokinetics, mechanisms of action and therapeutic application of drugs. This edition provides the latest information on molecular pharmacology as it redefines the definitive database of pharmacologic therapeutics. All the newly approved drugs are included. More importantly, for each drug class, there is an overview of chemical composition, mechanisms of action, indications and contraindications, clinical applications and potential side-effects.
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The Dynamics of Drug Absorption Distribution and Elimination
Mechanisms of Drug Action and the Relationship Between Drug
Principles of Therapeutics
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5-HT receptor 8-adrenergic absorption acid action activity administration adrenergic agonists amines anesthesia anesthetic antagonists antidepressants antipsychotic atropine autonomic Baldessarini barbiturates benzodiazepines binding blockade blood flow blood pressure brain carbamazepine cardiac cardiovascular catecholamines cause cells ceptors channels Chapter chemical cholinergic Clin clinical clonidine compounds concentrations decrease depolarization depression diazepam disease disorders dopamine dosage doses drug efficacy enflurane enzyme epinephrine ethanol excretion fibers function GABA GABAA receptor ganglia ganglionic gastrointestinal gene therapy gene transfer half-life halothane hepatic hypotension increase inhalation inhibition inhibitors injection interactions intravenous isoflurane liver local anesthetics mechanisms mediated membrane metabolism metabolites molecular muscarinic receptors nerve nervous system neuroleptic neuromuscular neurons nicotinic nitrous oxide norepinephrine occur oral oxygen patients peripheral pharmacokinetic Pharmacol pharmacological phenobarbital phenytoin plasma potential produce proteins release respiratory response result seizures serotonin side effects smooth muscle spinal stimulation subtypes subunits sympathetic synaptic therapeutic tion tissues toxicity transmitter treatment tricyclic tumor vascular