Cellular and Molecular Immunology
The new edition of this text continues the tradition of delivering an accessible, engaging, and current introduction to this essential subject. It describes the principles of basic and applied immunology in a concise, straightforward manner, while incorporating a wealth of current information. Over 330 new, full-color illustrations help readers grasp important information quickly and easily.
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INTRODUCTION TO IMMUNOLOGY
RECOGNITION OF ANTIGENS
MATURATION ACTIVATION AND REGULATION OF LYMPHOCYTES
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adhesion alleles amino acid anti antibodies antigen receptors antigen recognition APCs apoptosis autoimmune bacteria bind bone marrow called CD4+ T cells CD8+ cell activation cell receptor cell responses cell surface cell-mediated immunity cellular Chapter chemokines class II MHC costimulators CTLs cytes cytokines cytoplasmic dendritic cells differentiation disease domains effector functions encoding endothelial cells enzymes expression Fc receptors gene graft heavy chain helper T cells host humoral immune IFN-y immune system immunodeficiency Immunology induce infection inflammation inhibit innate immunity integrins interactions intracellular isotype kinase leukocytes ligand light chain lymph nodes lymphocytes lymphoid macrophages major histocompatibility complex mast cells mature mechanisms mediated membrane MHC molecules microbes mouse mutations neutrophils NK cells normal pathway peptides phagocytes phagocytosis plasma produced proliferation protein antigens proteins reactions recognize recombination regions role secreted sequences signals specific stimulate target cells thymocytes tion tissues transcription factors tumor viral virus