Melanocytic Tumors: A Guide to DiagnosisDetermining whether a melanocytic tumour is malignant or benign continues to be a key clinical challenge. This volume begins with the basic considerations, then goes on to describe the clinical and microscopic appearances of commomly encountered lesions - from nevi to metastatic melanoma. Commentary explores histology, diagnostic technique, prognosis, differential diagnosis and variants of cutaneous melanoma. |
Common terms and phrases
abundant acral actinic adjacent antibodies appearance approach arise assessment associated atypia atypical basal benign biopsy blue nevus Cancer Chapter characteristic Clark clinical Cochran combined common common nevi compound congenital contain cutaneous cytology cytoplasm deep dermal dermis develop diagnosis diameter differentiation difficult dysplastic nevus early epidermis epithelioid et al evaluation examination excision extension fibrosis frequent halo histologic identify increase infiltrate invasive involve junctional lentigo maligna less levels light lymph nodes lymphoid malignant melanoma mela melanin melano melanocytic lesions melanoma cells melanosomes metastatic melanoma microscopic mitoses moderate nests nevocytes noma normal Note nuclear nuclei occur origin overlying Pathol patients pattern pigmented possible present primary melanoma prognosis proliferation prominent radial growth phase rare RECURRENT regression relatively resemble rete reticular ridges scar seen separate shape similar single skin solar spindle Spitz nevi spreading Stage stain superficial TABLE thickness tissue tumor cells usually variant