Goodman and Gilman's The Pharmacological Basis of Therapeutics**** A classic text, now in its 50th year, recommended as a first purchase by Brandon-Hill. The new edition reflects the impact of modern biology since the previous edition in 1985: novel drugs produced by recombinant DNA technology, detailed knowledge of the structure and function of dozens of receptors, major progress in rational drug design, and improved treatment from appreciation of the importance of interplay between pharmacodynamics and pharmacokinetics. Annotation copyrighted by Book News, Inc., Portland, OR |
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Page 322
... Oxygen by the Circulation . The delivery of adequate in- spired oxygen to normally ventilated and perfused alveoli results in normal arterial oxygen tension . However , the arterial blood may fail to deliver sufficient oxygen to the ...
... Oxygen by the Circulation . The delivery of adequate in- spired oxygen to normally ventilated and perfused alveoli results in normal arterial oxygen tension . However , the arterial blood may fail to deliver sufficient oxygen to the ...
Page 325
... oxygen uptake and dilution with water vapor and carbon dioxide reduce the P。 in the alveoli to about 100 torr ... oxygen at 1 or more atmos- pheres of ambient pressure raises the arterial Po , to many times its normal value . This ...
... oxygen uptake and dilution with water vapor and carbon dioxide reduce the P。 in the alveoli to about 100 torr ... oxygen at 1 or more atmos- pheres of ambient pressure raises the arterial Po , to many times its normal value . This ...
Page 326
... OXYGEN IN BLOOD * ARTERIAL OXYGEN CONTENT ( vol % ) MIXED VENOUS OXYGEN CONTENT ( vol % ) ARTERIAL OXYGEN TENSION MIXED VENOUS OXYGEN TENSION ( torr ) Bound to Dissolved Total Dissolved Hemoglobin Bound to Hemoglobin ( torr ) Total 30 ...
... OXYGEN IN BLOOD * ARTERIAL OXYGEN CONTENT ( vol % ) MIXED VENOUS OXYGEN CONTENT ( vol % ) ARTERIAL OXYGEN TENSION MIXED VENOUS OXYGEN TENSION ( torr ) Bound to Dissolved Total Dissolved Hemoglobin Bound to Hemoglobin ( torr ) Total 30 ...
Contents
SECTION | 1 |
MECHANISms of Drug ACTION AND THE RELATIONSHIP | 28 |
PRINCIPLES OF THERAPEUTICS | 40 |
Copyright | |
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absorption acid action activity acute administration adrenergic agonists alcohol alkaloids amines anesthesia Anesthesiology anesthetic anti-ChE agents antidepressants antipsychotic antipsychotic drugs arterial atropine autonomic B-adrenergic barbiturates benzodiazepines blockade blocking agents blood flow blood pressure brain carbon dioxide cardiac cardiovascular catecholamines cause cells central Chapter chlorpromazine cholinergic chronic clinical compounds concentration decrease depression diazepam disease dopamine dosage doses enflurane enzyme epinephrine excreted fibers function ganglia ganglionic gastrointestinal guanethidine halothane hepatic Hydrochloride hypotension increase inhalation inhibition inhibitors injection interaction intravenous isoproterenol levodopa lithium local anesthetics mechanism membrane metabolism metabolites morphine muscarinic nephrine nerve nervous system neuromuscular neurons nicotine nitrous oxide norepinephrine occur opioids oral oxygen patients peripheral Pharmacol pharmacological phenobarbital phenothiazines phenytoin Physiol plasma potential produce propranolol receptors release renal reserpine respiratory response result seizures side effects skeletal muscle sleep smooth muscle spinal stimulation sympathetic sympathomimetic synaptic Ther therapeutic therapy tion tissues toxicity transmitter treatment tricyclic usually