Methods in Cancer ResearchHarris Busch |
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Page 200
... tetrahydrofolate ; CHOFH , formyl tetrahydrofolate ; CH ̧FH , methyl tetrahydrofolate ; MTX , Methotrexate ; other abbreviations are standard ( IUPAC - IUB Commission on Biochemical Nomenclature , 1973 ) . reactions in Fig . 1 involves ...
... tetrahydrofolate ; CHOFH , formyl tetrahydrofolate ; CH ̧FH , methyl tetrahydrofolate ; MTX , Methotrexate ; other abbreviations are standard ( IUPAC - IUB Commission on Biochemical Nomenclature , 1973 ) . reactions in Fig . 1 involves ...
Page 203
... Tetrahydrofolate + formate + ATP → 10 - formyl - 5 , 6 , 7 , 8 - tetrahydrofolate + ADP + P¡ ( 4 ) The resulting 10 - formyl tetrahydrofolate is then converted by acidification to 5,10 - methenyl tetrahydrofolate , and the latter is ...
... Tetrahydrofolate + formate + ATP → 10 - formyl - 5 , 6 , 7 , 8 - tetrahydrofolate + ADP + P¡ ( 4 ) The resulting 10 - formyl tetrahydrofolate is then converted by acidification to 5,10 - methenyl tetrahydrofolate , and the latter is ...
Page 345
... tetrahydrofolate , 203 Methionine , 110 , 218 biosynthesis , 199-200 Methotrexate ( MTX ) , 10-14 , 15 , 18 , 19-20 ... tetrahydrofolate and , 199-200 5,10 - Methylene - 5,6,7,8 - tetrahydrofolate , 200 N - Methyl - N ' - nitro - N ...
... tetrahydrofolate , 203 Methionine , 110 , 218 biosynthesis , 199-200 Methotrexate ( MTX ) , 10-14 , 15 , 18 , 19-20 ... tetrahydrofolate and , 199-200 5,10 - Methylene - 5,6,7,8 - tetrahydrofolate , 200 N - Methyl - N ' - nitro - N ...
Contents
CHAPTER I | 1 |
Wilms Tumor Wataru W Sutow I Introduction II Clinical Aspects III Treatment IV National Wilms Tumor Study V Miscellaneous Considerations Re... | 29 |
Receptors | 67 |
Copyright | |
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Acad acid activity added addition antibody antigen approach assay assumptions binding Biochem Biol bound buffer Cancer centrifuged challenge Chem chromatography column complex concentration containing curves cytoplasmic damping demonstrated described determined developed dihydrofolate reductases diploid cells effect enzyme et al experimental experiments extraction fraction function glucocorticoid growth hormone hosts immunity increase incubation indicated induced inhibition initial inoculation isolation labeled lines liver MCA-F mean measured method mice minutes mixture mRNA muscle Nature observed obtained patients period polysomes population prepared present Proc procedure proportion protein reaction recently receptor relative reported resistance response sensitive showed similar soluble solution specific steroid studies suggested synthesis Table tetraploid cells tissues translation transplantation treated treatment TSTA tumor cells values vincristine vitro volume