Cancers of the Head and Neck: Advances in Surgical Therapy, Radiation Therapy and Chemotherapy
Springer, May 31, 1987 - Medical - 294 pages
Cancers of the head and neck are among the most morbid of cancers. Convention al surgery and/or radiation therapy have a high cure rate for patients with early stage disease. However, despite optimal treatment with surgery and radiotherapy, patients with nodal spread or extensive local disease have a low cure rate. Even if a cancer is cured, a patient is often left with long-term debilities from the treatment and/or cancer. The major causes for decreased survival in patients with advanced head and neck cancer include local recurrence, distant metastases, and second primaries. All of these need to be addressed if one is to improve upon the curability of advanced disease. There are several new techniques, surgical and radiotherapeutic, designed to improve local control. Brachytherapy, or interstitial implantation, delivers a high dose of localized radiation with minimal normal tissue injury. This technique as discussed by Goffinet, may be even more efficacious when combined with hyperthermia. New, creative methods of radiation therapy delivery, such as the use of multiple fractions per day, as discussed by Parsons and Million, are also contributing to long-term local control. Laser therapy, discussed by Ossoff and Nemeroff, provides another tool for treatment of local disease.
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Laser Surgery for head and neck cancer
Advances in radiation therapyradiology
Brachytherapy head and neck cancer
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advanced head base tongue Biol biopsy bone carbon dioxide laser cervical chemotherapy Clin clinical trials combined commissure demonstrated diagnosis differentiation disease effects Epstein-Barr virus evaluation excision extended vertical partial Figure flap fractionation glottic glottic carcinoma head and neck histologic implants induction chemotherapy interaction interferon invasion involvement irradiation ISBN larynx lesions lymphatic lymphocytic malignant melanoma mandibular metastases modality mucosal muscle nasopharyngeal carcinoma neck cancer neck dissection neck nodes neoplasms nodal number of patients Oncol Oncology oral cavity orbital RMS oropharynx Otolaryngol partial laryngectomy patients with head perichondrium posterior postoperative primary tumor radiation therapy radical neck dissection radiotherapy randomized reconstruction recurrence relapse reported resection response retinoic acid retinoids rhabdomyosarcoma significant sinus squamous cell carcinoma statistical supraglottic supraglottic laryngectomy Surg surgery surgical T2-weighted Table technique thyroid cartilage treated treatment groups tumor twice-a-day vertical partial laryngectomy vitamin vocal cord