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The assessment of new drugs
Factors influencing the action of drugs
Adverse effects of drugs and therapeutic drug monitoring
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absorbed absorption acetylators acetylcholine acid acting activity acute administration adrenaline adrenergic adverse effects agents agonist analgesic antagonists anti anti-inflammatory antibiotics anticholinergic anticoagulants antidepressants antihistamine benzodiazepine blockade blocking drugs blood pressure calcium cardiac cause cells central chronic clinical compounds concentration corticosteroids deficiency depression derivatives diabetes diarrhoea diazepam digoxin disease diuretic dopamine dosage dose duration of action enzyme excreted folic acid gastric gastrointestinal given half-life hepatic histamine hormone hypertension hypnotic hypotension increase infections inhibit inhibitors insulin intravenous less levels levodopa liver membrane metabolism metabolites monoamine morphine nausea nerve neurone noradrenaline normal occur oestrogen oral P-receptor pain parenterally particularly pathway patients penicillin peripheral pharmacological phenobarbitone phenothiazines phenytoin plasma potassium potential produce progestogen properties propranolol prostaglandins protein reactions receptors reduced release renal resistance respiratory response serum smooth muscle sodium soluble steroids stimulation substances sulphonamides sympathetic sympathomimetic syndrome synthesis synthetic therapeutic therapy thiazide tissue toxicity treating treatment tricyclic urine vitamin vomiting warfarin