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A. E. T. Chiou ablation algorithm analysis apoptosis axial biological tissues Biomedical Optics blood cancer cells Chen China clinical concentration dermal detection detector Diagnostics and Treatment diffuse reflectance distribution dynamic effect energy excitation experimental fiber Figure fluorescence lifetime imaging fluorescence spectra function Fuzhou Gaussian beam glucose gold colloid human increase infrared intensity interaction laser beam layer LELI light source liver measurement method microscope Monte Carlo simulations near-infrared NIRS noninvasive Normal Univ obtained OCT system optical coherence tomography optical properties Optics in Health output oxygen parameters particles PCA-NN peak photoacoustic photobleaching photons probe Proc protein Raman reconstruction refractive index resolution root canal sample scanning scattering coefficient Science SERS signal skin solution South China Normal spatially resolved diffuse spectroscopy spectrum SPIE Vol surface technique Technology China temperature therapy thermal Tianjin tumor ultrasound vivo Wang wavelength x-ray