Juvenile Hormones and Juvenoids: Modeling Biological Effects and Environmental Fate

Front Cover
James Devillers
CRC Press, May 6, 2013 - Science - 401 pages
Juvenile hormones (JHs) are a group of structurally related sesquiterpenes secreted by the insect corpora allata. They affect most insect life-cycle stages and physiological functions, including embryogenesis, larval and adult development, metamorphosis, reproduction, metabolism, diapause, polyethism, and migration. Juvenoids such as methoprene, hy
 

Contents

A Historical Survey
1
2 Future Perspectives for Research on the Biosynthesis of Juvenile Hormones and Related Sesquiterpenoids in Arthropod Endocrinology and Ecotoxi...
15
Proximate Mechanisms Underlying Adaptive Genetic Modification of JH Regulation
31
4 SoldierSpecific Organ Developments Induced by a Juvenile Hormone Analog in a Nasute Termite
67
5 Roles of Juvenile Hormone Analog Methoprene in Gene Transcription
83
Linking Evolution Ecology and Management
99
7 Population Dynamics Models for Assessing the Endocrine Disruption Potential of Juvenile Hormone Analogues on Nontarget Species
127
8 SAR and QSAR Modeling of Juvenile Hormone Mimics
145
9 Using CoMFA and CoMSIA as Tools in a 3D QSAR Analysis of Juvenile Hormone Agonist Action in Drosophila
175
10 Predicting Highly Potent Juvenile Hormone Esterase Inhibitors from 2D QSAR Modeling
241
11 ReceptorGuided StructureActivity Modeling of Inhibitors of Juvenile Hormone Epoxide Hydrolases
267
12 Structural Studies of Juvenile Hormone Binding Proteins
291
13 In Silico Stereoelectronic Profile and Pharmacophore Similarity Analysis of Juvenile Hormone Juvenile Hormone Mimics IGRs and Insect Repelle...
311
14 Use of Multicriteria Analysis for Selecting Candidate Insecticides for Vector Control
347
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About the author (2013)

James Devillers has authored/edited 13 books and published more than 200 peer-reviewed papers and book chapters in QSAR and (eco)toxicology modeling. He is editor-in-chief of the journal SAR and QSAR in Environmental Research (Taylor & Francis) and editor of the series of books QSAR in Environmental and Health Sciences (CRC Press). James Devillers is also member of the editorial boards of Ecological Modelling (Elsevier), Xenobiotica (Taylor & Francis), and Current Bioactive Compounds (Bentham Science).

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