Bacterial Pathogenesis: A Molecular Approach
Bacterial Pathogenesis: A Molecular Approach is the first text designed to provide a comprehensive introduction to this dynamic field for both students and researchers. The application of molecular techniques to the study of bacterium-host interaction has made possible great progress in fundamental understanding of the molecular basis of infectious diseases. In the text the authors integrate material from pathogenic microbiology, molecular biology, immunology, and human physiology to provide a complete but accessible overview of the field.
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Pseudomembranous Colitis 282
Constitutive Nonspecific Defenses
Factors That Impair or Improve Host Defenses
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actin activity adherence adhesins ADP-ribosylation animal model antibiotics antibodies antigens aureus bacteria bacterial surface bacterium binding blood bloodstream botulinal toxin botulism capsule cause cell surface Chapter cholera toxin coli colonization complement complex components cultured cells cytokines cytoplasm damage develop diarrhea diphtheria toxin effect EHEC elicit enterocolitica enzymes EPEC strains ETEC exotoxin extracellular fever Figure food-borne disease genes encoding gonorrhoeae gram-negative gram-positive host cell host defenses human immune system important infection inflammatory ingested interaction intestinal invade invasin invasion iron kill Koch's postulates levels lung macrophages mammalian cells mice microflora molecule monocytogenes mucosal cells mutants normally occur operon pathogens peptide peptidoglycan pertussis phagocytes pili pilin plasmid PMNs pneumoniae prevent produce protective protein pyogenes receptor regulation regulatory resistance role Salmonella serum Shiga toxin Shigella Shigella spp slgA stimulate subunit symptoms target teria throat tion tissue toxic tract transcriptional transposon typhimurium vaccine virulence factors virulence genes Yersinia Yops