Cell to Cell Signals in Mammalian DevelopmentS.W. de Laat, J.G. Bluemink, C.L. Mummery Developmental biology deals with the regulatory principles underlying the generation of a new organism. The up-to-date knowledge of the molecular and cellular mechanisms that guide mammalian development from a single cell through a complex and integrated process of cell multiplication, differentiation and organisation of cells into tissues and organs is presented in this volume. Aspects of the molecular nature and developmental significance of cell-to-cell signals focus on: - hoxgenes, their products and potential role in mammalian morphogenesis; - growth factors, their receptors and signal transduction, and their role in guiding cell multiplication, differentiation and transformation; and - cell adhesion and extracellular matrix molecules, as short-range cell-to-cell signals in mammalian development. |
Contents
Structure Expression and Evolutionary Relationships | 9 |
Regulation of Expression of the Hox 2 3 Gene | 23 |
The Mouse En1 Gene Encodes a Nuclear Protein Expressed | 43 |
Copyright | |
21 other sections not shown
Other editions - View all
Cell to Cell Signals in Mammalian Development S.W. de Laat,J.G. Bluemink,C.L. Mummery Limited preview - 2013 |
Cell to Cell Signals in Mammalian Development S.W. de Laat,J.G. Bluemink,C.L. Mummery No preview available - 2011 |
Common terms and phrases
Acad Sci USA affinity amino acid analysis antibodies binding Biochem Biol Chem c-fos cDNA cell adhesion molecule Cell Biol cell lines cell surface cellular chromosome clones cluster conserved containing CSF-1 receptor culture cytoplasmic developmental differentiation domain Drosophila Edelman EGF receptor EGFR EMBO embryogenesis embryonal carcinoma embryos encodes endoderm epidermal growth factor exon expression extracellular fibroblasts function genomic growth factor receptor Gruss homeo homeobox genes homeodomain homology human hybridization induced insulin receptor interactions ligand membrane mesoderm mitogenic molecular mouse embryos mRNA murine N-CAM Natl Acad Sci NCAM neural cell adhesion neurons Northern blot NRK cells oncogene pattern PDGF phosphorylation polypeptide probe Proc Natl Acad protein region regulation retinoic acid role Schlessinger sequence Signals in Mammalian specific spinal cord stimulation structure TGFB TGFß tissues transcripts tyrosine kinase activity uvomorulin v-fms virus vitro Wolgemuth Xenopus