An Essay on the Shaking Palsy

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Whittingham and Rowland, 1817 - Parkinson's disease - 66 pages

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Page i - involuntary tremulous motion, with lessened muscular power in parts not in action, and even when supported; with a propensity to bend the trunk forwards, and to pass from a walking to a running pace ; the senses and intellect being uninjured.
Page 31 - Remarks on that Kind of Palsy of the Lower Limbs, which is Frequently Found to Accompany a Curvature of the Spine and is Supposed to be Caused by it.
Page 1 - In this stage, the sleep becomes much disturbed. The tremulous motion of the limbs occur during sleep, and augment until they awaken the patient, and frequently with much agitation and alarm. The power of conveying the food to the mouth is at length so much impeded that he is obliged to consent to be fed by others.
Page 41 - ... was so sensible, that solids could not be swallowed, on account of the pain they occasioned. Where the medulla in the back was completely divided, there was momentary loss of sight, loss of memory for fifteen . minutes, and permanent insensibility in all the lower parts of the body. The skin above the division of the spinal marrow perspired ; that below did not. The wounded spinal marrow appeared to be extremely sensible.
Page vi - At this stage the patient seldom experiences a suspension of the agitation of his limbs. Commencing, for instance, in one arm, the wearisome agitation is borne until beyond sufferance, when, by suddenly changing the posture, it is for a time stopped in that limb, to commence, generally, in less than a minute in one of the legs, or in the arm, of the other side.
Page 40 - ... the medulla spinalis in the neck, by coagulated blood, produced paralytic affections of the arms and legs, all the functions of the internal organs were carried on for thirty-five days, but the urine and stools passed involuntarily. Blood extravasated in the central part of the medulla in the neck, was attended with paralytic affection of the legs, but not of the arms. In a case where the substance of the medulla was lacerated in the neck, there was paralysis in all the parts...
Page 26 - These are, tremor tremulentus, the trembling consequent to indulgence in the drinking of spirituous liquors; that which proceeds from the immoderate employment of tea and coffee; that which appears to be dependent on advanced age; and all those tremblings which proceed from the various circumstances which induce a diminution of power in the nervous system. But by attending to that circumstance alone, which has been already noted as characteristic of mere tremor, the distinction will readily be made....
Page iv - ... think of his being the subject of disease, except when reminded of it by the unsteadiness of his hand, whilst writing or employing himself in any nicer kind of manipulation. But as the disease proceeds, similar employments are accomplished with considerable difficulty, the hand failing to answer with exactness to the dictates of the will. Walking becomes a task which cannot be performed without considerable attention. The legs are not raised to that height, or with that promptitude which the...
Page 3 - ... and hence is continually draining from the mouth, mixed with the particles of food, which he is no longer able to clear from the inside of the mouth. As the debility increases and the influence of the will over the muscles fades away, the tremulous agitation becomes more vehement. It now seldom leaves him for a moment ; but even when exhausted nature seizes a small portion of sleep, the motion becomes so violent as not only to shake the bed-hangings, but even the floor and sashes of the room.
Page iv - Sometimes whilst sitting dr standing. Sometime after the appearance of this symptom, and during its slow increase, one of the legs is discovered slightly to tremble, and is also found to suffer fatigue sooner than the leg of the other side : and in a few months this limb becomes agitated by similar tremblings, and suffers a similar loss of power.

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