Casarett & Doull's Toxicology: The Basic Science of Poisons, Seventh Edition
|
Contents
Unit 2 Disposition of Toxicants | 129 |
Unit 3 NonOrganDirected Toxicity | 327 |
Unit 4 Target Organ Toxicity | 453 |
Copyright | |
4 other sections not shown
Other editions - View all
Common terms and phrases
absorption acid activity addition agents alterations animals appears aromatic assays associated binding blood cancer carcinogens catalyzed cause cells cellular changes chemical chromosome compartment compounds concentration conjugation contain cytochrome P450 damage decrease detected determined developmental differences dose drugs effects elimination enzymes et al evaluation example excretion exposure expression factors Figure formation function gene genetic glucuronide glutathione growth half-life Health human important increased individuals induced inhibition inhibitors initial interactions involved known lead levels liver lung major mechanisms membrane metabolism metabolites mice molecules mouse mutagenic mutations normal observed occur organ oxidase oxidative oxygen pathway Pharmacol placenta plasma potential produce proteins rats reactions reactive receptor reduction relatively repair response risk risk assessment role shown signaling species structure studies substrates Table tion tissue toxicity Toxicol toxicology transport tumor vitro whereas xenobiotics