Anaesthetic Physiology and Pharmacology
Churchill Livingstone, 1997 - Medical - 779 pages
This book is a one-volume text covering the basic knowledge required by the anaesthesia trainee. Focusing on the pharmacology and physiology relevant to anaesthesia, this book is an indispensable aid to trainee anaesthetists who until now have had to buy separate textbooks of pharmacology and physiology.
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Drug action at receptors
Pharmacodynamic aspects of drug action
45 other sections not shown
absorption action potential activity afferent agents agonist amino acids anaesthesia anaesthetic analgesia arterial benzodiazepines binding block blood flow blood pressure body brain bupivacaine calcium capillary carbon cardiac output cardiovascular cause cells cerebral channels circulation clinical decrease depolarisation depression desflurane diazepam digoxin diuretics dose drug effects enflurane enzyme excretion factors fentanyl fibres fluid function gastric glucose half-life halothane heart rate hepatic hormone hypertension hypotension hypoxia increase induced infusion inhibition inhibitors inotropic insulin intracellular intravenous ions isoflurane kidney lipid solubility liver lung mechanisms membrane metabolism metabolite mmHg molecules morphine muscle myocardial neonate nerve neurones nitrous oxide normal NSAIDs occur opioid oral oxide oxygen pain pathways patients peripheral pethidine Pharmacokinetics plasma concentration platelet potassium produce prolonged propofol protein pulmonary receptors reduced reflex release renal failure resistance respiratory response result sensory sevoflurane side-effects sodium spinal stimulation synaptic therapy thiopentone tion tissue toxicity treatment trial vascular vasoconstriction venous ventricular volume