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" RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without an appreciable risk of deleterious effects during a lifetime. "
Methodology for deriving ambient water quality criteria for the protection ... - Page 2-14
2003
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Alaskan Oil Industry: Hearing Before the Subcommittee on ..., Volume 4

United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Transportation and Hazardous Materials - Petroleum industry and trade - 1989 - 206 pages
...measure is used when ground water is the main exposure pathway. • RfD (Reference Dose): "The RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without...
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Resource Conservation and Recovery Act Reauthorization: Hearing ..., Part 1

United States. Congress. House. Committee on Energy and Commerce. Subcommittee on Transportation and Hazardous Materials - Excise tax - 1990 - 620 pages
...measure is used when ground water is the main exposure pathway. • RID (Reference Dose): "The RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without...
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IRISChemical Information Database

Lawrence H. Keith - Science - 1992 - 166 pages
...equation: RfD = NOAEL / (UF x MF) which is the functional equivalent of Equation 1. In general, the RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without...
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Regulating Drinking Water Quality

Charles E. Gilbert, Edward J. Calabrese - Technology & Engineering - 1991 - 350 pages
...toxicants.6 RfDs are derived for the noncarcinogenic effects of chemicals that are also carcinogenic. The RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without...
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Superfund Risk Assessment in Soil Contamination Studies, Volume 1

Keith B. Hoddinott - Science - 1992 - 338 pages
...reference dose (RfD) for the purpose of quantitative risk assessment of noncarcinogenic chemicals. The RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of the daily exposure to the human population (including sensitive subgroups) that is likely to be without...
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The Use of the Benchmark Dose Approach in Health Risk Assessment

Kenny S. Crump - Carcinogenesis - 1995 - 104 pages
...other scientific information in setting standards for noncancer human health effects. An RfD or RfC is an estimate (with uncertainty spanning perhaps an order of magnitude) of daily exposure (RfD) or continuous inhalation exposure (RfC) to the human population (including sensitive subgroups)...
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Safe Drinking Water Act Amendments of 1995: Hearing Before the Committee on ...

United States. Congress. Senate. Committee on Environment and Public Works - Law - 1996 - 608 pages
...(which should be similar to MCLGs) uses less strong language and is as follows: The reference dose is an estimate (with uncertainty spanning perhaps...exposure to the human population (including sensitive groups) that is likely to be without appreciable risk of deleterious effects during a lifetime. We...
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Hazardous Waste Site Operations: A Training Manual for Site Professionals

Michael F. Waxman - Technology & Engineering - 1996 - 460 pages
...body weight per day — for example, 0.004 mg/kg/day. Simply described, an RfD is a rough estimate of daily exposure to the human population (including sensitive subgroups) that is likely to be without appreciable risk of deleterious effects during a lifetime. The uncertainty in...
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Departments of Veterans Affairs and Housing and Urban Development and ...

United States. Congress. Senate. Committee on Appropriations. Subcommittee on VA-HUD-Independent Agencies - Political Science - 1997 - 1090 pages
...procedure for a margin of exposure analysis for a response related to carcinogenicity is -An RfD or RfC is an estimate with uncertainty spanning perhaps an...availability of chronic as opposed to subchronic data. operationally analogous, the difference being that a threshold of cancer response is not necessarily...
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Wastewater Reclamation and Reuse: Water Quality Management Library, Volume 10

Takashi Asano - Technology & Engineering - 1998 - 1570 pages
...epidemiological data, animal studies, and other available toxicological information. In general, the RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without...
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