 | Lawrence H. Keith - Science - 1992 - 166 pages
...equation: RfD = NOAEL / (UF x MF) which is the functional equivalent of Equation 1. In general, the RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without... | |
 | Charles E. Gilbert, Edward J. Calabrese - Technology & Engineering - 1991 - 350 pages
...toxicants.6 RfDs are derived for the noncarcinogenic effects of chemicals that are also carcinogenic. The RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without... | |
 | Keith B. Hoddinott - Science - 1992 - 338 pages
...reference dose (RfD) for the purpose of quantitative risk assessment of noncarcinogenic chemicals. The RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of the daily exposure to the human population (including sensitive subgroups) that is likely to be without... | |
 | Kenny S. Crump - Carcinogenesis - 1995 - 104 pages
...other scientific information in setting standards for noncancer human health effects. An RfD or RfC is an estimate (with uncertainty spanning perhaps an order of magnitude) of daily exposure (RfD) or continuous inhalation exposure (RfC) to the human population (including sensitive subgroups)... | |
 | United States. Congress. Senate. Committee on Environment and Public Works - Law - 1996 - 608 pages
...(which should be similar to MCLGs) uses less strong language and is as follows: The reference dose is an estimate (with uncertainty spanning perhaps...exposure to the human population (including sensitive groups) that is likely to be without appreciable risk of deleterious effects during a lifetime. We... | |
 | Michael F. Waxman - Technology & Engineering - 1996 - 460 pages
...body weight per day — for example, 0.004 mg/kg/day. Simply described, an RfD is a rough estimate of daily exposure to the human population (including sensitive subgroups) that is likely to be without appreciable risk of deleterious effects during a lifetime. The uncertainty in... | |
 | Takashi Asano - Technology & Engineering - 1998 - 1570 pages
...epidemiological data, animal studies, and other available toxicological information. In general, the RfD is an estimate (with uncertainty spanning perhaps an order of magnitude) of a daily exposure to the human population (including sensitive subgroups) that is likely to be without... | |
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